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CD16b Protein, Human, Recombinant (hFc & His)
(Synonyms: Low affinity immunoglobulin γ Fc region receptor III-B, Low affinity immunoglobulin gamma Fc region receptor III-B, IgG Fc receptor III-1, Fc-γ RIII-beta, FcR-10, FCGR3B, FCGR3, Fc-gamma RIII-β, Fc-gamma RIII-beta, FCG3, CD16b) Copy Product InfoSynonyms: Low affinity immunoglobulin γ Fc region receptor III-B, Low affinity immunoglobulin gamma Fc region receptor III-B, IgG Fc receptor III-1, Fc-γ RIII-beta, FcR-10, FCGR3B, FCGR3, Fc-gamma RIII-β, Fc-gamma RIII-beta, FCG3, CD16b
Catalog No. TMPJ-00419 Copy Product Info
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $72 | 7-10 days | 7-10 days | |
| 10 μg | $116 | 7-10 days | 7-10 days | |
| 20 μg | $176 | 7-10 days | 7-10 days | |
| 50 μg | $310 | 7-10 days | 7-10 days | |
| 100 μg | $532 | 7-10 days | 7-10 days | |
| 200 μg | $919 | 7-10 days | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc-6xHis |
| Accession Number | O75015 |
| Amino Acid | Gly17-Gln208 |
| Construction | Gly17-Gln208 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Low affinity immunoglobulin γ Fc region receptor III-B, Low affinity immunoglobulin gamma Fc region receptor III-B, IgG Fc receptor III-1, Fc-γ RIII-beta, FcR-10, FCGR3B, FCGR3, Fc-gamma RIII-β, Fc-gamma RIII-beta, FCG3, CD16b |
| Research Background |
| Molecular Weight | 70 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: CD16b Protein, Human, Recombinant (hFc & His) chemical structure | CD16b Protein, Human, Recombinant (hFc & His) molecular weight
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