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CD16b Protein, Human, Recombinant (hFc & His)

Catalog No. TMPJ-00419
Synonyms: Fc-γ RIII-beta, FCG3, FcR-10, Fc-gamma RIII-β, FCGR3, FCGR3B, Low affinity immunoglobulin gamma Fc region receptor III-B, IgG Fc receptor III-1, Low affinity immunoglobulin γ Fc region receptor III-B, Fc-gamma RIII-beta, CD16b

Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CD16b Protein, Human, Recombinant (hFc & His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 116.00
50 μg 5 days $ 310.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Species Human
Expression System Human Cells
Tag C-Fc-6His
Accession Number O75015
Synonyms Fc-γ RIII-beta, FCG3, FcR-10, Fc-gamma RIII-β, FCGR3, FCGR3B, Low affinity immunoglobulin gamma Fc region receptor III-B, IgG Fc receptor III-1, Low affinity immunoglobulin γ Fc region receptor III-B, Fc-gamma RIII-beta, CD16b
Amino Acid Gly17-Gln208
Construction Recombinant Human Low Affinity Immunoglobulin Gamma Fc Region Receptor III-B is produced by our Mammalian expression system and the target gene encoding Gly17-Gln208 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 70 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

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Keywords

CD16b Protein, Human, Recombinant (hFc & His) Fc-γ RIII-beta FCG 3 FCG3 FcR-10 Fc-gamma RIII-β FCGR3 FCGR3B Low affinity immunoglobulin gamma Fc region receptor III-B IgG Fc receptor III-1 Low affinity immunoglobulin γ Fc region receptor III-B FCGR-3 FCG-3 Fc-gamma RIII-beta FCGR 3 CD16b recombinant recombinant-proteins proteins protein

 

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