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CD16b Protein, Human, Recombinant (hFc & His)

(Synonyms: Low affinity immunoglobulin γ Fc region receptor III-B, Low affinity immunoglobulin gamma Fc region receptor III-B, IgG Fc receptor III-1, Fc-γ RIII-beta, FcR-10, FCGR3B, FCGR3, Fc-gamma RIII-β, Fc-gamma RIII-beta, FCG3, CD16b) Copy Product Info

Synonyms: Low affinity immunoglobulin γ Fc region receptor III-B, Low affinity immunoglobulin gamma Fc region receptor III-B, IgG Fc receptor III-1, Fc-γ RIII-beta, FcR-10, FCGR3B, FCGR3, Fc-gamma RIII-β, Fc-gamma RIII-beta, FCG3, CD16b

Catalog No. TMPJ-00419 Copy Product Info
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Species
Human
Expression System
HEK293 Cells
TagC-hFc-6xHis
Accession NumberO75015
Amino AcidGly17-Gln208
ConstructionGly17-Gln208
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsLow affinity immunoglobulin γ Fc region receptor III-B, Low affinity immunoglobulin gamma Fc region receptor III-B, IgG Fc receptor III-1, Fc-γ RIII-beta, FcR-10, FCGR3B, FCGR3, Fc-gamma RIII-β, Fc-gamma RIII-beta, FCG3, CD16b
Research Background
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Chemical Properties
Molecular Weight70 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: CD16b Protein, Human, Recombinant (hFc & His) chemical structure | CD16b Protein, Human, Recombinant (hFc & His) molecular weight