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Synonyms: NEWENTRY, KAL6, HH6, HBGF-8, fibroblast growth factor 8 (androgen-induced), FGF-8, AIGF

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $59 | - | In Stock | |
| 10 μg | $94 | - | In Stock | |
| 20 μg | $152 | - | In Stock | |
| 50 μg | $297 | - | In Stock | |
| 100 μg | $506 | 7-10 days | 7-10 days | |
| 200 μg | $860 | 7-10 days | 7-10 days |
| Description | In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P55075-3 |
| Construction | A DNA sequence encoding the human FGF8b (P55075-3) (Gln23-Arg215) was expressed with an initial Met. |
| Protein Purity | > 95 % as determined by SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. . Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | NEWENTRY, KAL6, HH6, HBGF-8, fibroblast growth factor 8 (androgen-induced), FGF-8, AIGF |
| Research Background |
| Molecular Weight | The recombinant human FGF8b consists 194 amino acids and predicts a molecular mass of 22.5 kDa. |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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