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Spadin Acetate

Name: Spadin Acetate
Brand: TargetMol
SKU: T22178L
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22178L

Alias Spadin Acetate(1270083-24-3 Free base)

Spadin Acetate is a natural peptide derived from a propeptide released in blood. Spadin Acetate is able to block the TREK-1 channel activity. Spadin Acetate binds specifically to TREK-1 with an affinity of 10 nM.

Spadin Acetate

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Purity: 96.49%

Catalog No. T22178LAlias Spadin Acetate(1270083-24-3 Free base)

Pack Size	Price	Availability
1 mg	$98	In Stock
2 mg	$187	In Stock
5 mg	$295	In Stock
10 mg	$430	In Stock
25 mg	$672	In Stock
50 mg	$888	In Stock
100 mg	$1,180	In Stock
200 mg	$1,580	In Stock
1 mL x 10 mM (in DMSO)	$732	In Stock

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Batch Information

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Purity:96.49%

Resource Download

COA HPLC MS

Product Introduction

Bioactivity

Description	Spadin Acetate is a natural peptide derived from a propeptide released in blood. Spadin Acetate is able to block the TREK-1 channel activity. Spadin Acetate binds specifically to TREK-1 with an affinity of 10 nM.
Synonyms	Spadin Acetate(1270083-24-3 Free base)

Chemical Properties

Molecular Weight	2072.37
Formula	C₉₈H₁₄₆N₂₆O₂₄
Smiles	CC(O)=O.N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CO)NC([C@H](C(C)C)NC(CNC([C@H]([C@@H](C)CC)NC([C@H]3N(C(CNC([C@H](CO)NC([C@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CCCNC(N)=N)NC([C@H]6N(C([C@H](CC(C)C)NC([C@H]7N(C([C@H](C)NC([C@H](CC8=CC=C(O)C=C8)N)=O)=O)CCC7)=O)=O)CCC6)=O)=O)=O)=O)=O)CCC3)=O)=O)=O)=O)=O)=O)=O)=O
Relative Density.	no data available
Color	White
Appearance	Solid
Sequence	H-Tyr-Ala-Pro-Leu-Pro-Arg-Trp-Ser-Gly-Pro-Ile-Gly-Val-Ser-Trp-Gly-Leu-Arg-OH.
Sequence Short	YAPLPRWSGPIGVSWGLR

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (26.54 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.4825 mL	2.4127 mL	4.8254 mL	24.1270 mL
5 mM	0.0965 mL	0.4825 mL	0.9651 mL	4.8254 mL
10 mM	0.0483 mL	0.2413 mL	0.4825 mL	2.4127 mL
20 mM	0.0241 mL	0.1206 mL	0.2413 mL	1.2063 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc