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Anti-CSEN Antibody (5I474) is a Rabbit antibody targeting CSEN. Anti-CSEN Antibody (5I474) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-CSEN Antibody (5I474) is a Rabbit antibody targeting CSEN. Anti-CSEN Antibody (5I474) can be used in IHC-P. |
Alias | Kv channel interacting protein 3, calsenilin, KCHIP3, DREAM, CSEN |
Ig Type | Monoclonal Rabbit IgG |
Clone | 5I474 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human KCNIP3 in human liver with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:250-1:1000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CSEN / calsenilin / KCNIP3 (rh CSEN / calsenilin / KCNIP3; TMPY-03615; Q9Y2W7-1; Met1-Ile256). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3, also known as CSEN) is a Protein Coding gene. CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. CSEN also functions as a calcium-regulated transcriptional repressor and interacts with presenilins. CSEN binds to the DRE element of genes including PDYN and FOS. CSEN is broadly expressed in the brain, thyroid, and other tissues. Diseases associated with KCNIP3 include Alzheimer's Disease and Niemann-Pick Disease, Type C2. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human CSEN / calsenilin / KCNIP3 Protein (TMPY-03615) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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