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Biotin-PEG4-Amide-C6-Azide

Name: Biotin-PEG4-Amide-C6-Azide
Brand: TargetMol
SKU: T17580
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T17580Cas No. 1006592-62-6

Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Biotin-PEG4-Amide-C6-Azide

🥰Excellent

Purity: 99.19%

Catalog No. T17580Cas No. 1006592-62-6

Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$51	In Stock
10 mg	$76	In Stock
25 mg	$127	In Stock
50 mg	$172	In Stock
100 mg	$255	In Stock
200 mg	$378	In Stock
1 mL x 10 mM (in DMSO)	$75	In Stock

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Questions

Batch Information

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Purity:99.19%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker utilized in PROTAC synthesis.
In vitro	PROTACs comprise two distinct ligands linked together: one ligand binds to an E3 ubiquitin ligase, and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1].

Chemical Properties

Molecular Weight	615.79
Formula	C₂₇H₄₉N₇O₇S
Cas No.	1006592-62-6
Smiles	C(CCCC(NCCOCCOCCOCCOCCC(NCCCCCCN=[N+]=[N-])=O)=O)[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (162.39 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6239 mL	8.1197 mL	16.2393 mL	81.1965 mL
5 mM	0.3248 mL	1.6239 mL	3.2479 mL	16.2393 mL
10 mM	0.1624 mL	0.8120 mL	1.6239 mL	8.1197 mL
20 mM	0.0812 mL	0.4060 mL	0.8120 mL	4.0598 mL
50 mM	0.0325 mL	0.1624 mL	0.3248 mL	1.6239 mL
100 mM	0.0162 mL	0.0812 mL	0.1624 mL	0.8120 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc