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TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi)

(Synonyms: TRAIL-R, TRAIL R1, TNFRSF10A, MGC9365, DR4, CD261, APO2) Copy Product Info

Synonyms: TRAIL-R, TRAIL R1, TNFRSF10A, MGC9365, DR4, CD261, APO2

Catalog No. TMPK-00706 Copy Product Info
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$437-10 days7-10 days
10 µg$667-10 days7-10 days
20 µg$1057-10 days7-10 days
50 µg$1977-10 days7-10 days
100 µg$3367-10 days7-10 days
200 µg$5967-10 days7-10 days
500 µg$1,3507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Human TRAIL R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human TRAIL, No Tag with an affinity constant of 1.02 nM as determined in SPR assay.
Description
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberO00220
ConstructionPro34-Asn239
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTRAIL-R, TRAIL R1, TNFRSF10A, MGC9365, DR4, CD261, APO2
Research Background
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily.The expression of apoptosis-inducing TRAIL-R1 and TRAIL-R2 and of the decoy receptors TRAIL-R3 and TRAIL-R4 was systematically studied in all developmental stages of peripheral B cells isolated from the blood and secondary lymphoid organs. Expression of TRAIL-Rs is modulated along development, with highest levels observed in germinal center B cells.
Chemical Properties
Molecular Weight24.7 kDa (predicted). Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi) chemical structure | TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi) molecular weight