Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-VCAM-1 Antibody-HRP (8I177)

😃Good
Catalog No. TMAY-00286H
Alias VCAM-1, vascular cell adhesion molecule 1, INCAM-100, CD106

Anti-VCAM-1 Antibody-HRP (8I177) is a HRP-conjugated Mouse antibody targeting VCAM-1. Anti-VCAM-1 Antibody-HRP (8I177) can be used in ELISA.

Anti-VCAM-1 Antibody-HRP (8I177)

Anti-VCAM-1 Antibody-HRP (8I177)

😃Good
Catalog No. TMAY-00286HAlias VCAM-1, vascular cell adhesion molecule 1, INCAM-100, CD106
Anti-VCAM-1 Antibody-HRP (8I177) is a HRP-conjugated Mouse antibody targeting VCAM-1. Anti-VCAM-1 Antibody-HRP (8I177) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μg$294 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-VCAM-1 Antibody-HRP (8I177) is a HRP-conjugated Mouse antibody targeting VCAM-1. Anti-VCAM-1 Antibody-HRP (8I177) can be used in ELISA.
AliasVCAM-1, vascular cell adhesion molecule 1, INCAM-100, CD106
Ig Type
Monoclonal Mouse IgG1
Clone
8I177
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VCAM1/VCAM-1/CD106 (rh VCAM1/VCAM-1/CD106; NP_001069.1Met1-Pro697). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundVascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains are generated by alternative splicing, with the longer form predominant. VCAM-1 is an endothelial ligand for very late antigen-4 (VLA-4) and α4ß7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is induced on endothelial cells during inflammatory bowel disease, atherosclerosis, allograft rejection, infection, and asthmatic responses. During these responses, VCAM-1 forms a scaffold for leukocyte migration. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. VCAM-1 has been identified as a potential anti-inflammatory therapeutic target, the hypothesis being that reduced expression of VCAM-1 will slow the development of atherosclerosis. In addition, VCAM-1-activated signals in endothelial cells are regulated by cytokines indicating that it is important to consider both endothelial cell adhesion molecule expression and function during inflammatory processes.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
HRP
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human VCAM1/VCAM-1/CD106 Protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-VCAM-1 Antibody-HRP (8I177) | purchase Anti-VCAM-1 Antibody-HRP (8I177) | Anti-VCAM-1 Antibody-HRP (8I177) cost | order Anti-VCAM-1 Antibody-HRP (8I177)