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Anti-ITGAE Polyclonal Antibody
(Synonyms: Mucosal lymphocyte 1 antigen, MGC183601, Itgae, ITAE, Integrin alpha-IEL, integrin alpha-E precursor, Integrin alpha-E heavy chain, Integrin alpha-E, HML-1 antigen, CD103, antigen CD103, human mucosal lymphocyte antigen 1, aM290, alpha-M290, alpha-E1, alpha polypeptide, A530055J10) Copy Product Info
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Synonyms: Mucosal lymphocyte 1 antigen, MGC183601, Itgae, ITAE, Integrin alpha-IEL, integrin alpha-E precursor, Integrin alpha-E heavy chain, Integrin alpha-E, HML-1 antigen, CD103, antigen CD103, human mucosal lymphocyte antigen 1, aM290, alpha-M290, alpha-E1, alpha polypeptide, A530055J10
Catalog No. TMAB-00993 Copy Product Info
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Anti-ITGAE Polyclonal Antibody is a Rabbit antibody targeting ITGAE. Anti-ITGAE Polyclonal Antibody can be used in FCM,WB.
Anti-ITGAE Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ITGAE Polyclonal Antibody is a Rabbit antibody targeting ITGAE. Anti-ITGAE Polyclonal Antibody can be used in FCM,WB. |
| Synonyms | Mucosal lymphocyte 1 antigen, MGC183601, Itgae, ITAE, Integrin alpha-IEL, integrin alpha-E precursor, Integrin alpha-E heavy chain, Integrin alpha-E, HML-1 antigen, CD103, antigen CD103, human mucosal lymphocyte antigen 1, aM290, alpha-M290, alpha-E1, alpha polypeptide, A530055J10 |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1ug/test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human Integrin alpha-E heavy chain |
| Antigen Species | Human |
| Gene Name | ITGAE |
| Gene ID | |
| Protein Name | Integrin alpha-E |
| Uniprot ID | |
| Biology Area | Regulatory T Cells,Adhesion,Alpha,T Lymphocytic Lineage |
| Function | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
| Molecular Weight | Theoretical: 110/128 kDa. Actual: 110/128 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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