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Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody

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Catalog No. TMAC-01050

Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cyclin H (Thr315). Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody can be used in WB.

Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody

Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody

😃Good
Catalog No. TMAC-01050
Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cyclin H (Thr315). Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2177-10 days
100 μL$3167-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cyclin H (Thr315). Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundRegulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of threonine 315 (E-W-T(p)-D-D) derived from Human Cyclin H
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 36 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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