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Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody (Synonyms: p-Cyclin H (Thr315), p-Cyclin H (T315), Cyclin H...)
Catalog No. TMAC-01050 Copy Product Info
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Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cyclin H (Thr315). Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody can be used in WB.
Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAC-01050
Synonyms p-Cyclin H (Thr315), p-Cyclin H (T315), Cyclin H (p-Thr315), Cyclin H (p-T315)
Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cyclin H (Thr315). Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody can be used in WB.
Anti-Phospho-Cyclin H
(Thr315) Polyclonal Antibody
(Thr315) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cyclin H (Thr315). Anti-Phospho-Cyclin H (Thr315) Polyclonal Antibody can be used in WB. |
| Synonyms | p-Cyclin H (Thr315), p-Cyclin H (T315), Cyclin H (p-Thr315), Cyclin H (p-T315) |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of extracts from JK cells (Lane 2), using Cyclin H (Phospho-Thr315) Antibody TMAC-01050. The lane on the left is treated with antigen-specific peptide.  |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 315 (E-W-T(p)-D-D) derived from Human Cyclin H |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 36 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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