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Synonyms: Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 μg | $35 | 35 days | 35 days | |
| 20 μg | $51 | 35 days | 35 days | |
| 50 μg | $91 | 35 days | 35 days | |
| 100 μg | $168 | 35 days | 35 days | |
| 200 μg | $325 | 35 days | 35 days | |
| 500 μg | $781 | 35 days | 35 days | |
| 1 mg | $1,120 | 35 days | 35 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-GST |
| Accession Number | P62256 |
| Amino Acid | Met1-Leu183 |
| Construction | Met1-Leu183 |
| Protein Purity | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2 |
| Research Background |
| Molecular Weight | 50 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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