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UBE2H Protein, Human, Recombinant (GST)

(Synonyms: Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2) Copy Product Info

Synonyms: Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2

Catalog No. TMPJ-01047 Copy Product Info
Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.
UBE2H Protein, Human, Recombinant (GST)
Pack SizePriceUSA StockGlobal StockQuantity
10 μg$3535 days35 days
20 μg$5135 days35 days
50 μg$9135 days35 days
100 μg$16835 days35 days
200 μg$32535 days35 days
500 μg$78135 days35 days
1 mg$1,12035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 90% as determined by reducing SDS-PAGE.
Appearance:Solution
Color:Transparent
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.
Species
Human
Expression System
E. coli
TagN-GST
Accession NumberP62256
Amino AcidMet1-Leu183
ConstructionMet1-Leu183
Protein Purity
Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsUbiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2
Research Background
Chemical Properties
Molecular Weight50 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Related Tags: UBE2H Protein, Human, Recombinant (GST) chemical structure | UBE2H Protein, Human, Recombinant (GST) molecular weight