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Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody
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Catalog No. TMAC-01315
Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EphA2/3/4 (Tyr588/596). Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody can be used in WB,IF.
Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody
Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody
😃Good
Catalog No. TMAC-01315
Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EphA2/3/4 (Tyr588/596). Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody can be used in WB,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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| Description | Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EphA2/3/4 (Tyr588/596). Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody can be used in WB,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-1000; IF: 1:100-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | 11690 |
| Antigen Species | Peptide sequence around phosphorylation site of tyrosine 588/596 (K-T-Y(p)-V-R)/(R-T-Y(p)-V-D) derived from Human EPHA2/3/4 |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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