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Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody (Synonyms: p-EphA2/3/4 (Y588/596), p-EphA2/3/4 (Tyr588/...)

Catalog No. TMAC-01315 Copy Product Info
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Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EphA2/3/4 (Tyr588/596). Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody can be used in IF,WB.

Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-01315
Synonyms p-EphA2/3/4 (Y588/596), p-EphA2/3/4 (Tyr588/596), EphA2/3/4 (p-Y588/596), EphA2/3/4 (p-Tyr588/596)

Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EphA2/3/4 (Tyr588/596). Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody can be used in IF,WB.

Anti-Phospho-EphA2/3/4
(Tyr588/596) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3187-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EphA2/3/4 (Tyr588/596). Anti-Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody can be used in IF,WB.
Synonymsp-EphA2/3/4 (Y588/596), p-EphA2/3/4 (Tyr588/596), EphA2/3/4 (p-Y588/596), EphA2/3/4 (p-Tyr588/596)
Ig Type
IgG
Reactivity
Human,Mouse
Verified Activity
1. Western blot analysis of extracts from HepG2 cells using EPHA2/3/4 (Phospho-Tyr588/596) Antibody TMAC-01315. The lane on the right is treated with the antigen-specific peptide.
2. Immunofluorescence staining of methanol-fixed HeLa cells using EPHA2/3/4 (Phospho-Tyr588/596) Antibody TMAC-01315.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IF: 1:100-200
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundReceptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 588/596 (K-T-Y(p)-V-R)/(R-T-Y(p)-V-D) derived from Human EPHA2/3/4
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 130 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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