Follistatin Protein, Human, Recombinant (His)

Name: Follistatin Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-07024
Rating: 4.5 (1 reviews)

(Synonyms: FS) Copy Product Info

Synonyms: FS

Catalog No. TMPY-07024 Copy Product Info

Follistatin Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is P19883-1.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$68	7-10 days	7-10 days
10 µg	$112	7-10 days	7-10 days
20 µg	$188	7-10 days	7-10 days
50 µg	$370	7-10 days	7-10 days
100 µg	$715	7-10 days	7-10 days
200 µg	$987	7-10 days	7-10 days
500 µg	$1,980	7-10 days	7-10 days
1 mg	$3,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation.The ED50 for this effect is typically 5-40 ng/mL.
Description	Follistatin Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is P19883-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P19883-1
Construction	A DNA sequence encoding the human FST (NP_037541.1) (Met1-Asp329) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity	> 85% as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	FS
Research Background	Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. follistatin are expressed and subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal, bone marrow, and placenta but perhaps most notably in anterior pituitary-the classical target tissue for inhibin, the activin-follistatin system may play a key role in early embryogenesis. Follistatin binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone follistatin is a binding protein to activin. Since activin binds to follistatin, it is imperative to determine the nature of the activin/follistatin binding complex.

Chemical Properties

Molecular Weight

34.4 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.