Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 1,620.00 | |
500 μg | 5 days | $ 6,520.00 | |
1 mg | 5 days | $ 10,870.00 |
Description | Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
Species | Cynomolgus |
Expression System | HEK293 |
Accession Number | A0A2K5W6I7 |
Synonyms | MGC129713, GPRC5D, MGC129714, orphan G-protein coupled receptor |
Construction | Recombinant Cynomolgus GPRC5D Protein-VLP is expressed from HEK293. It contains Met1-Cys300.[Accession |A0A2K5W6I7] |
Protein Purity | > 95% as determined by HPLC |
Molecular Weight | The target protein has a predicted MW of 35.10 kDa. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant. |
Stability & Storage |
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
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GPRC5D Protein-VLP, Cynomolgus, Recombinant MGC129713 MGC-129713 MGC 129714 MGC-129714 GPRC5D MGC129714 MGC 129713 orphan G-protein coupled receptor recombinant recombinant-proteins proteins protein