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GPRC5D Protein-VLP, Cynomolgus, Recombinant

Catalog No. TMPK-00528
Synonyms: MGC129713, GPRC5D, MGC129714, orphan G-protein coupled receptor

Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.

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GPRC5D Protein-VLP, Cynomolgus, Recombinant
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 1,620.00
500 μg 5 days $ 6,520.00
1 mg 5 days $ 10,870.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
Species Cynomolgus
Expression System HEK293
Accession Number A0A2K5W6I7
Synonyms MGC129713, GPRC5D, MGC129714, orphan G-protein coupled receptor
Construction Recombinant Cynomolgus GPRC5D Protein-VLP is expressed from HEK293. It contains Met1-Cys300.[Accession |A0A2K5W6I7]
Protein Purity > 95% as determined by HPLC
Molecular Weight The target protein has a predicted MW of 35.10 kDa.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Supplied as 0.22μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant.
Stability & Storage

Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.

References and Literature

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Keywords

GPRC5D Protein-VLP, Cynomolgus, Recombinant MGC129713 MGC-129713 MGC 129714 MGC-129714 GPRC5D MGC129714 MGC 129713 orphan G-protein coupled receptor recombinant recombinant-proteins proteins protein

 

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