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Anti-ICAM-2/CD102 Antibody (9W742)
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Catalog No. TMAY-00621
Alias Ly-60, intercellular adhesion molecule 2, Icam-2, CD102
Anti-ICAM-2/CD102 Antibody (9W742) is a Mouse antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (9W742) can be used in IHC-P.
Anti-ICAM-2/CD102 Antibody (9W742)
Anti-ICAM-2/CD102 Antibody (9W742)
😃Good
Catalog No. TMAY-00621Alias Ly-60, intercellular adhesion molecule 2, Icam-2, CD102
Anti-ICAM-2/CD102 Antibody (9W742) is a Mouse antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (9W742) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: IHC-P Reactivity: Human |
| Alias | Ly-60, intercellular adhesion molecule 2, Icam-2, CD102 |
| Ig Type | Mouse IgG1 |
| Clone | 9W742 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human ICAM2 in human spleen with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to vascular endothelial cells. 2. Immunochemical staining of human ICAM2 in human kidney with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to vascular endothelial cells. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ICAM-2 / CD102 (rh ICAM-2 / CD102; TMPY-01418; NP_000864.2; Met1-Gln223). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ICAM-2 / CD102 protein (TMPY-01418) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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