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Anti-ICAM-2/CD102 Antibody (9W742)

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Catalog No. TMAY-00621
Alias Ly-60, intercellular adhesion molecule 2, Icam-2, CD102

Anti-ICAM-2/CD102 Antibody (9W742) is a Mouse antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (9W742) can be used in IHC-P.

Anti-ICAM-2/CD102 Antibody (9W742)

Anti-ICAM-2/CD102 Antibody (9W742)

😃Good
Catalog No. TMAY-00621Alias Ly-60, intercellular adhesion molecule 2, Icam-2, CD102
Anti-ICAM-2/CD102 Antibody (9W742) is a Mouse antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (9W742) can be used in IHC-P.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-ICAM-2/CD102 Antibody (9W742) is a Mouse antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (9W742) can be used in IHC-P.
AliasLy-60, intercellular adhesion molecule 2, Icam-2, CD102
Ig Type
Monoclonal Mouse IgG1
Clone
9W742
Reactivity
Human
Verified Activity
1. Immunochemical staining of human ICAM2 in human spleen with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to vascular endothelial cells.

2. Immunochemical staining of human ICAM2 in human kidney with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to vascular endothelial cells.
Application
IHC-P
Recommended Dose
IHC-P: 1:50-1:200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ICAM-2 / CD102 (rh ICAM-2 / CD102; TMPY-01418; NP_000864.2; Met1-Gln223). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIntercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human ICAM-2 / CD102 protein (TMPY-01418)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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