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Anti-Phospho-CASP9 (Thr125) Polyclonal Antibody 2 (Synonyms: p-CASP9 (Thr125), p-CASP9 (T125), CASP9 (p-Thr125...)

Catalog No. TMAC-00573 Copy Product Info
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Anti-Phospho-CASP9 (Thr125) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CASP9 (Thr125). Anti-Phospho-CASP9 (Thr125) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-CASP9 (Thr125) Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAC-00573
Synonyms p-CASP9 (Thr125), p-CASP9 (T125), CASP9 (p-Thr125), CASP9 (p-T125)

Anti-Phospho-CASP9 (Thr125) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CASP9 (Thr125). Anti-Phospho-CASP9 (Thr125) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-CASP9
(Thr125) Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-CASP9 (Thr125) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CASP9 (Thr125). Anti-Phospho-CASP9 (Thr125) Polyclonal Antibody can be used in IHC,WB.
Synonymsp-CASP9 (Thr125), p-CASP9 (T125), CASP9 (p-Thr125), CASP9 (p-T125)
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Western blot analysis of extracts from HeLa cells treated with TNF using Caspase 9 (Phospho-Thr125) Antibody TMAC-00573. The lane on the right is treated with the antigen-specific peptide.
2. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Caspase 9 (Phospho-Thr125) antibody TMAC-00573 (left) or the same antibody preincubated with blocking peptide (right).
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundInvolved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of threonine 125 (P-E-T(p)-P-R) derived from Human Caspase 9
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 47 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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