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1H-Pyrazole-3-carboxylic acid

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Catalog No. T7842Cas No. 1621-91-6

1H-Pyrazole-3-carboxylic acid is an important intermediate in the synthesis of various pharmaceuticals and agricultural chemicals and is also used in the synthesis of compounds such as pyrazolones, pyrazole amides, and pyrazolines.

1H-Pyrazole-3-carboxylic acid

1H-Pyrazole-3-carboxylic acid

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Purity: 99.69%
Catalog No. T7842Cas No. 1621-91-6
1H-Pyrazole-3-carboxylic acid is an important intermediate in the synthesis of various pharmaceuticals and agricultural chemicals and is also used in the synthesis of compounds such as pyrazolones, pyrazole amides, and pyrazolines.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
200 mg$29-In Stock
500 mg$29-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.69%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
1H-Pyrazole-3-carboxylic acid is an important intermediate in the synthesis of various pharmaceuticals and agricultural chemicals and is also used in the synthesis of compounds such as pyrazolones, pyrazole amides, and pyrazolines.
Chemical Properties
Molecular Weight112.0868
FormulaC4H4N2O2
Cas No.1621-91-6
SmilesOC(=O)C1=CC=NN1
Relative Density.1.524 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 27.5 mg/mL (245.35 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM8.9217 mL44.6083 mL89.2166 mL446.0829 mL
5 mM1.7843 mL8.9217 mL17.8433 mL89.2166 mL
10 mM0.8922 mL4.4608 mL8.9217 mL44.6083 mL
20 mM0.4461 mL2.2304 mL4.4608 mL22.3041 mL
50 mM0.1784 mL0.8922 mL1.7843 mL8.9217 mL
100 mM0.0892 mL0.4461 mL0.8922 mL4.4608 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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