CD200R1/CRTR2 Protein, Human, Recombinant (His)

Name: CD200R1/CRTR2 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00233
Rating: 4.5 (1 reviews)

(Synonyms: OX2R, MOX2R, CRTR2, Cell Surface Glycoprotein OX2 Receptor 1, Cell Surface Glycoprotein CD200 Receptor 1, CD200R1, CD200R, CD200 Cell Surface Glycoprotein Receptor) Copy Product Info

Synonyms: OX2R, MOX2R, CRTR2, Cell Surface Glycoprotein OX2 Receptor 1, Cell Surface Glycoprotein CD200 Receptor 1, CD200R1, CD200R, CD200 Cell Surface Glycoprotein Receptor

Catalog No. TMPJ-00233 Copy Product Info

Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.

CD200R1/CRTR2 Protein, Human, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$61	7-10 days	7-10 days
10 µg	$97	7-10 days	7-10 days
20 µg	$148	7-10 days	7-10 days
50 µg	$272	7-10 days	7-10 days
100 µg	$485	7-10 days	7-10 days
200 µg	$869	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	Q8TD46-4
Amino Acid	Ala27-Leu266
Construction	Ala27-Leu266
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	OX2R, MOX2R, CRTR2, Cell Surface Glycoprotein OX2 Receptor 1, Cell Surface Glycoprotein CD200 Receptor 1, CD200R1, CD200R, CD200 Cell Surface Glycoprotein Receptor
Research Background	Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.

Chemical Properties

Molecular Weight

50-80 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.