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CD200R1/CRTR2 Protein, Human, Recombinant (His)

(Synonyms: OX2R, MOX2R, CRTR2, Cell Surface Glycoprotein OX2 Receptor 1, Cell Surface Glycoprotein CD200 Receptor 1, CD200R1, CD200R, CD200 Cell Surface Glycoprotein Receptor) Copy Product Info

Synonyms: OX2R, MOX2R, CRTR2, Cell Surface Glycoprotein OX2 Receptor 1, Cell Surface Glycoprotein CD200 Receptor 1, CD200R1, CD200R, CD200 Cell Surface Glycoprotein Receptor

Catalog No. TMPJ-00233 Copy Product Info
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$617-10 days7-10 days
10 μg$977-10 days7-10 days
20 μg$1487-10 days7-10 days
50 μg$2727-10 days7-10 days
100 μg$4857-10 days7-10 days
200 μg$8697-10 days7-10 days
500 μg$1,9007-10 days7-10 days
1 mg$2,7307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.
Species
Human
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberQ8TD46-4
Amino AcidAla27-Leu266
ConstructionAla27-Leu266
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsOX2R, MOX2R, CRTR2, Cell Surface Glycoprotein OX2 Receptor 1, Cell Surface Glycoprotein CD200 Receptor 1, CD200R1, CD200R, CD200 Cell Surface Glycoprotein Receptor
Research Background
Chemical Properties
Molecular Weight50-80 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: CD200R1/CRTR2 Protein, Human, Recombinant (His) chemical structure | CD200R1/CRTR2 Protein, Human, Recombinant (His) molecular weight