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Anti-HMGB1 Polyclonal Antibody

(Synonyms: SBP-1, HMGB1, HMG3, HMG-1, HMG1) Copy Product Info
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Synonyms: SBP-1, HMGB1, HMG3, HMG-1, HMG1

Catalog No. TMAB-00870 Copy Product Info
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Anti-HMGB1 Polyclonal Antibody is a Rabbit antibody targeting HMGB1. Anti-HMGB1 Polyclonal Antibody can be used in FCM.
Anti-HMGB1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HMGB1 Polyclonal Antibody is a Rabbit antibody targeting HMGB1. Anti-HMGB1 Polyclonal Antibody can be used in FCM.
SynonymsSBP-1, HMGB1, HMG3, HMG-1, HMG1
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Cow)
Application
Recommended Dose
FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Chromosome.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundHigh Mobility Group Box-1 (HMGB1) is a cytokine implicated in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. The cholinergic anti-inflammatory pathway, a vagus nerve dependent mechanism, inhibits HMGB1 release in experimental disease models
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human HMGB1
Antigen Species
Human
Gene Name
HMGB1
Gene ID
Protein Name
High mobility group protein B1
Uniprot ID
Biology Area
HMGs,HMG Box,SARS Coronavirus,hmgb1
Function
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
Chemical Properties
Molecular WeightTheoretical: 25 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Related Tags: Anti-HMGB1 Polyclonal Antibody molecular weight