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Anti-PIGR Antibody (5O982)
😃Good
Catalog No. TMAY-00318
Alias polymeric immunoglobulin receptor, Pigr
Anti-PIGR Antibody (5O982) is a Rabbit antibody targeting PIGR. Anti-PIGR Antibody (5O982) can be used in IHC-P,ICC/IF.
Anti-PIGR Antibody (5O982)
Anti-PIGR Antibody (5O982)
😃Good
Catalog No. TMAY-00318Alias polymeric immunoglobulin receptor, Pigr
Anti-PIGR Antibody (5O982) is a Rabbit antibody targeting PIGR. Anti-PIGR Antibody (5O982) can be used in IHC-P,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $94 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: IHC-P, ICC/IF Reactivity: Human |
| Alias | polymeric immunoglobulin receptor, Pigr |
| Ig Type | Rabbit IgG |
| Clone | 5O982 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human PIGR in human liver (cirrhosis) with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte. 2. Immunochemical staining of human PIGR in human breast carcinoma with rabbit monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 3. Immunofluorescence staining of PIGR in HepG2 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-Y PIGR monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm. |
| Application | IHC-P,ICC/IF |
| Recommended Dose | IHC-P: 1:50-1:200; ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PIGR (rh PIGR; TMPY-00902; NP_002635.2; Met1-Arg638,365Ser/Gly). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human PIGR protein (TMPY-00902) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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