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PAR-2 Activating Peptide acetate

🥰Excellent
Catalog No. TP1046L
Alias SLIGRL-NH2 acetate, Protease-Activated Receptor-2 Activating Peptide acetate, PAR-2 Activating Peptide acetate(171436-38-7 free base)

PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).

PAR-2 Activating Peptide acetate
Other Forms of PAR-2 Activating Peptide acetate:

PAR-2 Activating Peptide acetate

🥰Excellent
Purity: 99.92%
Catalog No. TP1046LAlias SLIGRL-NH2 acetate, Protease-Activated Receptor-2 Activating Peptide acetate, PAR-2 Activating Peptide acetate(171436-38-7 free base)
PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).
Pack SizePriceAvailabilityQuantity
1 mg$78In Stock
5 mg$205In Stock
10 mg$367In Stock
25 mg$619In Stock
50 mg$879In Stock
100 mg$1,190In Stock
200 mg$1,590In Stock
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Purity:99.92%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).
In vitro
Protease-Activated Receptor-2 Activating Peptide (SLIGRL-NH2) is an agonist of PAR-2 and MrgprC11[1]. Protease-Activated Receptor-2 Activating Peptide (SLIGRL-NH2) causes an L-NAME-inhibited relaxation. Based on SLIGRL-NH2 causing a concentration-dependent relaxation with an EC50 of 10 μM in endothelium-free preparations in the presence of perivascular adipose tissue (PVAT) , 20 μM is used as a suitable ‘test’ concentration of peptide in subsequent experiments designed to evaluate the effects of potential inhibitors of ADRF release/action. In the endothelium-free aorta preparations, SLIGRL-NH2 causes a concentration-dependent relaxation in preparations only in the presence of PVAT [+PVAT, -ENDO (endothelium)][2].
SynonymsSLIGRL-NH2 acetate, Protease-Activated Receptor-2 Activating Peptide acetate, PAR-2 Activating Peptide acetate(171436-38-7 free base)
Chemical Properties
Molecular Weight716.88
FormulaC31H60N10O9
SmilesCC[C@H](C)[C@@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)N.CC(=O)O
Relative Density.no data available
SequenceH-Ser-Leu-Ile-Gly-Arg-Leu-NH2.
Sequence ShortSLIGRL
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mM, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3949 mL6.9747 mL13.9493 mL69.7467 mL
5 mM0.2790 mL1.3949 mL2.7899 mL13.9493 mL
10 mM0.1395 mL0.6975 mL1.3949 mL6.9747 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

SLIGRL-NH2 AcetateProteaseactivatedReceptorProteaseactivated ReceptorPAR-2 Activating Peptide AcetatePAR2 Activating Peptide acetatePAR-2PAR 2 Activating Peptide acetate
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