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HER2-targeted peptide H6F is a molecule designed to bind to HER2 and target breast cancer cells, characterized by the amino acid sequence YLFFVFER. It can conjugate with the bifunctional chelator hydrazinonicotinamide (HYNIC) for binding with 99mTc for radiolabeling purposes. Single-photon emission computed tomography (SPECT) imaging demonstrates that the radiolabeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MB-453 tumor-bearing mouse models. This peptide is useful for studies in tumor molecular imaging.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | HER2-targeted peptide H6F is a molecule designed to bind to HER2 and target breast cancer cells, characterized by the amino acid sequence YLFFVFER. It can conjugate with the bifunctional chelator hydrazinonicotinamide (HYNIC) for binding with 99mTc for radiolabeling purposes. Single-photon emission computed tomography (SPECT) imaging demonstrates that the radiolabeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MB-453 tumor-bearing mouse models. This peptide is useful for studies in tumor molecular imaging. |
| Molecular Weight | 1120.3 |
| Formula | C58H77N11O12 |
| Cas No. | 1644155-35-0 |
| Smiles | [C@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CC(C)C)=O)=O)(CC3=CC=CC=C3)C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC(O)=O)=O)=O)C(C)C)=O |
| Sequence | Tyr-Leu-Phe-Phe-Val-Phe-Glu-Arg |
| Sequence Short | YLFFVFER |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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