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Vapendavir diphosphate
🥰Excellent
Catalog No. T13284Cas No. 1198151-75-5
Alias BTA798 diphosphate, BTA 798 diphosphate
Vapendavir diphosphate (BTA798 diphosphate) is a rhinoceros/enterovirus inhibitor that targets the hydrophobic pocket in the viral capsid and is a capsid-binding agent with antiviral activity that prevents viral entry into the cell. Vapendavir diphosphate inhibits EV71 replication.
Vapendavir diphosphate
🥰Excellent
Purity: 98.75%
Catalog No. T13284Alias BTA798 diphosphate, BTA 798 diphosphateCas No. 1198151-75-5
Vapendavir diphosphate (BTA798 diphosphate) is a rhinoceros/enterovirus inhibitor that targets the hydrophobic pocket in the viral capsid and is a capsid-binding agent with antiviral activity that prevents viral entry into the cell. Vapendavir diphosphate inhibits EV71 replication.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $399 | In Stock |
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Purity:98.75%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Vapendavir diphosphate (BTA798 diphosphate) is a rhinoceros/enterovirus inhibitor that targets the hydrophobic pocket in the viral capsid and is a capsid-binding agent with antiviral activity that prevents viral entry into the cell. Vapendavir diphosphate inhibits EV71 replication. |
| Targets&IC50 | EV71 (various strains):0.5-1.4 μM (EC50) |
| In vitro | Vapendavir diphosphate exhibits potent antiviral activity against enterovirus 71 (EV71) replication with EC50 values ranging from 0.5-1.4 μM for different EV71 strains. [1] Vapendavir diphosphate was able to effectively inhibit the replication of 21 EV71 strains/isolates representing different genomic groups A, B and C in vitro. [2] |
| Synonyms | BTA798 diphosphate, BTA 798 diphosphate |
| Molecular Weight | 578.45 |
| Formula | C21H32N4O11P2 |
| Cas No. | 1198151-75-5 |
| Smiles | O=P(O)(O)O.CCOC1=NOC2=C1C=CC(OCCC(CC3)CCN3C4=NN=C(C)C=C4)=C2.O=P(O)(O)O |
| Relative Density. | no data available |
| Color | Yellow |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||
| Solubility Information | DMSO: 4 mg/mL (6.92 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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