PTX3 Protein, Mouse, Recombinant (His)

Name: PTX3 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00981
Rating: 4.5 (1 reviews)

(Synonyms: α-induced protein 5, pentraxin-related protei, pentraxin-related gene, rapidly induced by IL-1 β, pentraxin-related gene, rapidly induced by IL-1 beta, pentraxin-3, pentraxin 3, long, Pentraxin 3, Pentaxin-related protein PTX3, pentaxin-related gene, rapidly induced by IL-1 β, tumor necrosis factor, pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5) Copy Product Info

Synonyms: α-induced protein 5, pentraxin-related protei, pentraxin-related gene, rapidly induced by IL-1 β, pentraxin-related gene, rapidly induced by IL-1 beta, pentraxin-3, pentraxin 3, long, Pentraxin 3, Pentaxin-related protein PTX3, pentaxin-related gene, rapidly induced by IL-1 β, tumor necrosis factor, pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5

Catalog No. TMPJ-00981 Copy Product Info

Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It's subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.

Pack Size	Price	USA Stock	Global Stock
10 µg	$183	7-10 days	7-10 days
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$792	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 90% as determined by reducing SDS-PAGE.

Appearance:Solution

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It's subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.
Species	Mouse
Expression System	HEK293 Cells
Tag	N-6xHis
Accession Number	P48759
Amino Acid	Glu18-Ser381
Construction	Glu18-Ser381
Protein Purity	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Synonyms	α-induced protein 5, pentraxin-related protei, pentraxin-related gene, rapidly induced by IL-1 β, pentraxin-related gene, rapidly induced by IL-1 beta, pentraxin-3, pentraxin 3, long, Pentraxin 3, Pentaxin-related protein PTX3, pentaxin-related gene, rapidly induced by IL-1 β, tumor necrosis factor, pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5
Research Background	Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.

Chemical Properties

Molecular Weight

54 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.