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TargetMol | Tags Metabolism
ANGPTL
(4)
ATP Citrate Lyase
(15)
Acetyl-CoA Carboxylase
(32)
Aconitase
(2)
Acyltransferase
(145)
Adenosine Deaminase
(16)
AhR
(31)
Amino Acids and Derivatives
(1026)
Aminopeptidase
(70)
Amylase
(41)
Angiotensin-converting Enzyme (ACE)
(172)
Apolipoprotein
(9)
CETP
(17)
CPT
(5)
Calcium Channel
(628)
Carbonic Anhydrase
(215)
Casein Kinase
(159)
Cytochromes P450
(491)
DHFR
(58)
Decarboxylase
(7)
Dehydrogenase
(468)
Drug Metabolite
(587)
Endogenous Metabolite
(3224)
Epoxide Hydrolase
(57)
FAAH
(72)
FABP
(15)
FXR
(78)
Factor VIII
(6)
Factor VIIa
(5)
Factor Xa
(92)
Fatty Acid Synthase
(70)
GSNOR
(3)
Glucokinase
(71)
Glucosidase
(219)
Glutathione Peroxidase
(73)
Glyoxalase
(17)
HIF/HIF Prolyl-Hydroxylase
(194)
HMG-CoA Reductase
(69)
HSP
(264)
Hexokinase
(9)
Hydrogenase
(2)
Hydroxylase
(45)
IDO
(94)
Indoleamine 2,3-Dioxygenase (IDO)
(98)
Isocitrate Dehydrogenase (IDH)
(46)
LDL
(26)
LDLR
(14)
Lipase
(37)
Lipid
(44)
Liposome
(442)
Lipoxygenase
(194)
Liver X Receptor
(51)
MAGL
(61)
MAO
(108)
Mitochondrial Metabolism
(212)
N-Acetylglucosaminyltransferase
(1)
NADPH
(62)
NAMPT
(44)
NEDD4-1
(3)
NEDD8
(8)
NUDIX hydrolase
(2)
Neprilysin
(31)
PAI-1
(38)
PDE
(528)
PGK1
(3)
PKM
(43)
PPAR
(386)
Phosphatase
(432)
Phospholipase
(201)
Phosphorylase
(21)
Photosystem (PS)
(5)
Procollagen C Proteinase
(1)
Prolyl Endopeptidase (PREP)
(33)
RAR/RXR
(12)
REV-ERB
(9)
ROR
(96)
Reactive Oxygen Species
(773)
Reductase
(121)
Retinoid Receptor
(109)
SGK
(24)
Serine/threonin kinase
(90)
Stearoyl-CoA Desaturase (SCD)
(29)
Taste receptor
(6)
Thioredoxin
(2)
Transaminase
(3)
Transferase
(222)
Transketolase
(9)
UGT
(17)
Vitamin
(89)
Xanthine Oxidase
(73)
glycosidase
(28)
hCE
(2)
stilbene oxidase
(1)
transporter
(87)

Lipid

The Lipid is a large class of organic compounds that are insoluble in water but soluble in organic solvents. They include fats, oils, hormones, and components of certain membranes. They are not only a source of energy, but also a key component of cellular structure and signaling.

Fatostatin
T9266125256-00-0
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs.
  • $30
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TargetMol | Citations Cited
NBD-PE
T86974178119-00-1
NBD-PE is a lipid dye used primarily as a probe to study lipid organisation and dynamics within cell membranes and also to study membrane fusion by fluorescence resonance energy transfer (FRET), Ex=463 nm, Em=536 nm.
  • $173
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Periplogenin
T4S1983514-39-6
1. Periplogenin (Desoxostrophanthidin) plays protective roles against thyrotoxicosis and associated cardiovascular problems, are mediated through its direct antithyroidal and/or LPO inhibiting properties.
  • $41
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TargetMol | Inhibitor Sale
WWL229
T89971338575-28-2
WWL229 is a selective inhibitor of Ces3, acting by inhibiting recombinant Ces3 while not affecting Ces1f, ABHD6, or other tested serine hydrolases, and replicating the effects of WWL113 in adipocytes.
  • $42
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Betulin
T3121473-98-3
Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is found in birch sap as well.
  • $33
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TargetMol | Citations Cited
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium
T3560690693-88-2
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) can be used in lipid mixtures with DOPC and DOPE as effective nontoxic and nonviral DNA vectors. It has been utilized in the formation of unilamellar vesicles to study membrane structure curvature and in supported lipid bilayers to examine the impact of various support materials on lipid redistribution between membrane leaflets.
  • $31
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VK-28
T9956312611-92-0
VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation.
  • $117
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Bakuchiol
T340010309-37-2
Bakuchiol possesses anti-tumor,and anti-helmenthic properties. It has cytotoxic activity, mainly due to its DNA polymerase1 inhibiting activity. Bakuchiol has anti-bacterial activity against oral pathogens, has great potential for use in food additives and mouthwash for preventing and treating dental caries.
  • $40
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DDAO
T15082118290-05-4
DDAO is a promising near-infrared (NIR) red fluorescent probe with a long emission wavelength (λem = 656 nm) and a tunable excitation wavelength (600-650 nm). It can be designed for detecting the activities of various enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin, and esterases.
  • $42
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Mevastatin
T068373573-88-3
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
  • $51
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TargetMol | Citations Cited
Fenipentol
T0857583-03-9
Fenipentol (Pancoral) has the properties of Choleretics and Cholagogues.
  • $29
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Glutathione ethyl ester
T7861692614-59-0
Glutathione ethyl ester is a cell-permeable, modified form of glutathione (GSH) that undergoes rapid hydrolysis by esterases in vivo to restore GSH levels. It inhibits progression in the early stages of diabetes-associated cataract formation and reduces reactive oxygen species (ROS) content, thereby protecting in vitro mature bovine oocytes from oxidative stress.
  • $40
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Nevadensin
T572210176-66-6
Nevadensin is an important herb-based constituent inhibiting estragole bioactivation. Nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat. It also exhibits inhibition activity against Mycobacterium tuberculosis, with equal MIC value of 200 microg/mL.
  • $39
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Atractylodin
T366655290-63-6
Atractylodin (Atractydin) has high lipase inhibitory activity (IC5:39.12 μM); Atractylodin possesses strong repellency activities against T. castaneum adults (LD50: 1.83 μg/cm). The repellency of Atractylodin (0.63 μg/cm) can achieve >90%.
  • $39
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Carboxylesterase-IN-2
T775242764748-88-9
Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.
  • $56
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HSL-IN-1
T115762095156-13-9
HSL-IN-1 is an orally active and highly potent hormone-sensitive lipase (HSL) inhibitor that significantly reduces the reactive metabolite load and can reduce the release of free fatty acids from stored fat.
  • $199
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PF 429242
T4317947303-87-9
PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO c
  • $37
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TargetMol | Citations Cited
3-Hydroxydodecanoic acid
T191201883-13-2
3-Hydroxydodecanoic acid is a long-chain fatty acid and endogenous metabolite that accumulates in rat brains, inducing oxidative stress, lipid peroxidation, and protein oxidative damage, while reducing GSH levels, making it useful for studying neurological symptoms.
  • $38
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Dehydrocholate sodium
T0516145-41-5
Dehydrocholate sodium, a hydrocholeretic, can increase bile output to clear increased bile acid load.
  • $42
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MSU-42011
T774992456434-36-7In house
MSU-42011 is an orally active retinoid X receptor-like (RXR) agonist. It potently inhibits the expression of iNOS, low SREBP-induced and activated RXR, and p-ERK at the protein level. MSU-42011 has demonstrated antitumor activity in a [kras]-driven mouse model of lung cancer and is effective for the treatment of preclinical [kras]-driven lung cancer with immunomodulatory activity.
  • $41
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Cetilistat
T3283282526-98-1
Cetilistat (ATL-962) is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
  • $29
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MAGL-IN-5
T9967359714-55-9
MAGL-IN-5 is a non-selective lipase inhibitor.
  • $30
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Lifibrol
T2783296609-16-4In house
Lifibrol (U-83860) is an inhibitor of cholesterol synthesis.Lifibrol has anticholesterol and hypolipidemic properties and promotes the conversion of LDL Apo B-100 in patients with hypercholesterolemia and mixed hyperlipidemia.
  • $88
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Carboxylesterase-IN-3
T607882764748-92-5In house
Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.
  • $39
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