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Anti-APOB48R Polyclonal Antibody
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Catalog No. TMAB-00130
Alias Apolipoprotein B48 receptor, Apolipoprotein B-100 receptor, Apolipoprotein B100 receptor, apoB-48R, apoB-100R, apoB100R, APOB, apo b-100
Anti-APOB48R Polyclonal Antibody is a Rabbit antibody targeting APOB48R. Anti-APOB48R Polyclonal Antibody can be used in WB.
Anti-APOB48R Polyclonal Antibody
Anti-APOB48R Polyclonal Antibody
😃Good
Catalog No. TMAB-00130Alias Apolipoprotein B48 receptor, Apolipoprotein B-100 receptor, Apolipoprotein B100 receptor, apoB-48R, apoB-100R, apoB100R, APOB, apo b-100
Anti-APOB48R Polyclonal Antibody is a Rabbit antibody targeting APOB48R. Anti-APOB48R Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-APOB48R Polyclonal Antibody is a Rabbit antibody targeting APOB48R. Anti-APOB48R Polyclonal Antibody can be used in WB. |
| Synonyms | Apolipoprotein B48 receptor, Apolipoprotein B-100 receptor, Apolipoprotein B100 receptor, apoB-48R, apoB-100R, apoB100R, APOB, apo b-100 |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Rabbit) |
| Verified Activity | 1. Sample: Blood (Mouse) Cell Lysate at 30 μg Primary: Anti-APOB48R (TMAB-00130) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 115 kDa Observed band size: 115 kDa 2. Sample: Spleen (Mouse) Lysate at 40 μg Primary: Anti-APOB48R (TMAB-00130) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 115 kDa Observed band size: 115 kDa   |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Peripheral membrane protein. Note=Binds monocyte-macrophage membrane. Thought to be anchored in the membrane through an interaction with an integral membrane protein. |
| Tissue Specificity | Expressed in peripheral blood leukocytes > bone marrow = spleen > lymph node, and only faintly visible in appendix and thymus. Expressed in the brain, heart, kidney, liver, lung, pancreas, and placenta. Expressed primarily by reticuloendothelial cells: mo |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | APOB48R is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG) rich lipoproteins. It may provide essential lipids, lipid soluble vitamins and other nutrients to reticuloendothelial cells. |
| Immunogen | KLH conjugated synthetic peptide: human APOB48R |
| Antigen Species | Human |
| Gene Name | APOBR |
| Gene ID | |
| Protein Name | Apolipoprotein B receptor |
| Uniprot ID | |
| Function | Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. |
| Molecular Weight | Theoretical: 115 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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