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Ardisiacrispin B

Name: Ardisiacrispin B
Brand: TargetMol
SKU: TN1397
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1397Cas No. 112766-96-8

Ardisiacrispin B is a natural triterpenoid saponin with anticancer activity that induces apoptosis and ferroptosis, exhibiting inhibitory effects against A549, HL-60, MDA-MB-231, and other cells.

Ardisiacrispin B

😃Good

Catalog No. TN1397Cas No. 112766-96-8

Ardisiacrispin B is a natural triterpenoid saponin with anticancer activity that induces apoptosis and ferroptosis, exhibiting inhibitory effects against A549, HL-60, MDA-MB-231, and other cells.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$98	-	In Stock
5 mg	$247	-	In Stock
10 mg	$369	-	In Stock
25 mg	$619	-	In Stock
50 mg	$883	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Appearance:Solid

Color:White

Resource Download

COA MS HNMR

Product Introduction

Bioactivity

Description

Ardisiacrispin B is a natural triterpenoid saponin with anticancer activity that induces apoptosis and ferroptosis, exhibiting inhibitory effects against A549, HL-60, MDA-MB-231, and other cells.

Chemical Properties

Molecular Weight	1075.25
Formula	C₅₃H₈₆O₂₂
Cas No.	112766-96-8
Smiles	[H][C@@]12C[C@](C)(CC[C@@]11CO[C@@]22CC[C@]3([H])[C@@]4(C)CC[C@H](O[C@@H]5OC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]6O[C@@H](C)[C@H](O)[C@@H](O)[C@H]6O)[C@H](O)[C@H]5O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]2(C)C[C@H]1O)C=O
Relative Density.	1.46 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80.00 mg/mL (74.40 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.9300 mL	4.6501 mL	9.3002 mL	46.5008 mL
5 mM	0.1860 mL	0.9300 mL	1.8600 mL	9.3002 mL
10 mM	0.0930 mL	0.4650 mL	0.9300 mL	4.6501 mL
20 mM	0.0465 mL	0.2325 mL	0.4650 mL	2.3250 mL
50 mM	0.0186 mL	0.0930 mL	0.1860 mL	0.9300 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc