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Clindamycin palmitate hydrochloride

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Catalog No. T6449Cas No. 25507-04-4
Alias Clindamycin palmitate HCl, Cleocin Pediatric

Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.

Clindamycin palmitate hydrochloride

Clindamycin palmitate hydrochloride

😃Good
Catalog No. T6449Alias Clindamycin palmitate HCl, Cleocin PediatricCas No. 25507-04-4
Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$23335 days35 days
100 mg$44035 days35 days
250 mg$98735 days35 days
500 mg$1,82035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.
In vivo
After treatment of Cefoperazone (2 g, i.v.), levels in serum range from 202μg/mL to 375 μg/mL depending on the period of drug administration. After intramuscular injection of 2 g of Cefoperazone, the mean peak serum level is 111 μg/mL at 1.5 hours. At 12 hours after dosing, mean serum levels are still 2 to 4 μg/mL. Cefoperazone is 90% bound to serum proteins.
SynonymsClindamycin palmitate HCl, Cleocin Pediatric
Chemical Properties
Molecular Weight699.85
FormulaC34H63ClN2O6S·HCl
Cas No.25507-04-4
SmilesCl.CCCCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](O)[C@@H](O)[C@H](O[C@@H]1SC)[C@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)[C@H](C)Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: Soluble
DMSO: 140 mg/mL (200.04 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Corn Oil: 3.3 mg/mL (4.72 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4289 mL7.1444 mL14.2888 mL71.4439 mL
5 mM0.2858 mL1.4289 mL2.8578 mL14.2888 mL
10 mM0.1429 mL0.7144 mL1.4289 mL7.1444 mL
20 mM0.0714 mL0.3572 mL0.7144 mL3.5722 mL
50 mM0.0286 mL0.1429 mL0.2858 mL1.4289 mL
100 mM0.0143 mL0.0714 mL0.1429 mL0.7144 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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