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4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)

(Synonyms: Tumor necrosis factor receptor superfamily member 9, Tnfrsf9, Secreted CD137 antigen) Copy Product Info

Synonyms: Tumor necrosis factor receptor superfamily member 9, Tnfrsf9, Secreted CD137 antigen

Catalog No. TMPJ-00145 Copy Product Info
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$11035 days35 days
20 µg$16935 days35 days
50 µg$31035 days35 days
100 µg$47535 days35 days
200 µg$73235 days35 days
500 µg$1,30035 days35 days
1 mg$1,98035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Species
Mouse
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP20334
Amino AcidVal24-Leu187
ConstructionVal24-Leu187
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
SynonymsTumor necrosis factor receptor superfamily member 9, Tnfrsf9, Secreted CD137 antigen
Research Background
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Chemical Properties
Molecular Weight60-70 KDa (reducing condition)
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc) chemical structure | 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc) molecular weight