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Anti-Aquaporin-4/AQP4 Antibody (8G264) (Alias: WCH4, Mercurial-insensitive water channel (MIWC), Aquaporin-...)

Catalog No. TMAB-00137 Copy Product Info
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Anti-Aquaporin-4/AQP4 Antibody (8G264) is a Mouse antibody targeting Aquaporin-4/AQP4. Anti-Aquaporin-4/AQP4 Antibody (8G264) can be used in IF,IHC-Fr,IHC-P.

Anti-Aquaporin-4/AQP4 Antibody (8G264)

Copy Product Info
😃Good
Catalog No. TMAB-00137
Alias WCH4, Mercurial-insensitive water channel (MIWC), Aquaporin-4, AQP-4, AQP4

Anti-Aquaporin-4/AQP4 Antibody (8G264) is a Mouse antibody targeting Aquaporin-4/AQP4. Anti-Aquaporin-4/AQP4 Antibody (8G264) can be used in IF,IHC-Fr,IHC-P.

Anti-Aquaporin-4/AQP4 Antibody (8G264)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
In stock · Dispatch: USA[1-2d] Global[5-7d]
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Aquaporin-4/AQP4 Antibody (8G264) is a Mouse antibody targeting Aquaporin-4/AQP4. Anti-Aquaporin-4/AQP4 Antibody (8G264) can be used in IF,IHC-Fr,IHC-P.
SynonymsWCH4, Mercurial-insensitive water channel (MIWC), Aquaporin-4, AQP-4, AQP4
Ig Type
IgG1
Clone
8G264
Reactivity
Human,Mouse,Rat
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (mouse lung); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Aquaporin 4) Monoclonal Antibody, Unconjugated (ascites of TMAB-00137) at 1:2000 overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Aquaporin 4) Monoclonal Antibody, Unconjugated (TMAB-00137) at 1:800 overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded (Human lung cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Aquaporin 4) Monoclonal Antibody, Unconjugated (TMAB-00137) at 1:800 overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Multi-pass membrane protein.
Tissue SpecificityBrain, muscle, heart, kidney, lung, and trachea.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
Recombinant Protein: human Aquaporin 4 Protein
Antigen Species
Human
Gene Name
AQP4
Gene ID
Protein Name
Aquaporin-4
Uniprot ID
Biology Area
Channels
Function
Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
Chemical Properties
Molecular WeightTheoretical: 36 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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