LAMP1 Protein, Human, Recombinant (hFc)

Name: LAMP1 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-00264
Rating: 4.5 (1 reviews)

(Synonyms: Lysosome-Associated Membrane Protein 1, Lysosome-Associated Membrane Glycoprotein 1, LAMP-1, LAMP1, CD107a, CD107 Antigen-Like Family Member A) Copy Product Info

Synonyms: Lysosome-Associated Membrane Protein 1, Lysosome-Associated Membrane Glycoprotein 1, LAMP-1, LAMP1, CD107a, CD107 Antigen-Like Family Member A

Catalog No. TMPJ-00264 Copy Product Info

Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.

Pack Size	Price	USA Stock	Global Stock
5 μg	$72	35 days	35 days
10 μg	$116	35 days	35 days
20 μg	$176	35 days	35 days
50 μg	$310	35 days	35 days
100 μg	$532	35 days	35 days
200 μg	$919	35 days	35 days
500 μg	$1,900	35 days	35 days
1 mg	$2,730	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P11279
Amino Acid	Ala29-Met382
Construction	Ala29-Met382
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonyms	Lysosome-Associated Membrane Protein 1, Lysosome-Associated Membrane Glycoprotein 1, LAMP-1, LAMP1, CD107a, CD107 Antigen-Like Family Member A
Research Background

Chemical Properties

Molecular Weight

90-130 KDa (reducing condition)

Storage & Solubility Information

Storage

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LAMP 1

Related Tags: LAMP1 Protein, Human, Recombinant (hFc) chemical structure | LAMP1 Protein, Human, Recombinant (hFc) molecular weight