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Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231)

(Synonyms: Phospho-Histone H2AX (S139), p-Histone H2AX (Ser139), p-Histone H2AX (S139), Histone H2AX (p-Ser139), Histone H2AX (p-S139)) Copy Product Info
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Synonyms: Phospho-Histone H2AX (S139), p-Histone H2AX (Ser139), p-Histone H2AX (S139), Histone H2AX (p-Ser139), Histone H2AX (p-S139)

Catalog No. TMAH-00904 Copy Product Info
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Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) is an antibody targeting Phospho-Histone H2AX (Ser139). Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) can be used in ELISA,WB.
Anti-Phospho-Histone H2AX
(Ser139) Antibody
(8H231)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) is an antibody targeting Phospho-Histone H2AX (Ser139). Anti-Phospho-Histone H2AX (Ser139) Antibody (8H231) can be used in ELISA,WB.
SynonymsPhospho-Histone H2AX (S139), p-Histone H2AX (Ser139), p-Histone H2AX (S139), Histone H2AX (p-Ser139), Histone H2AX (p-S139)
Ig Type
Rabbit IgG
Clone
8H231
Reactivity
Human
Application
Recommended Dose
WB:1:3000-1:10000.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus. Chromosome.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide
Antigen Species
Human
Gene Name
H2AFX
Gene ID
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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