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C5AR1 Protein-VLP, Human, Recombinant (His)

(Synonyms: CD88, C5R1, C5AR1, C5AR, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor (C5a-R;C5aR)) Copy Product Info

Synonyms: CD88, C5R1, C5AR1, C5AR, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor (C5a-R;C5aR)

Catalog No. TMPH-01022 Copy Product Info
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 41.1 kDa and the accession number is P21730.
C5AR1 Protein-VLP, Human, Recombinant (His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$27520 days20 days
10 μg$45920 days20 days
20 μg$77620 days20 days
50 μg$1,27020 days20 days
100 μg$1,87020 days20 days
200 μg$3,15020 days20 days
500 μg$6,28020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:/
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized human C5AR1 at 10 μg/mL can bind Anti-C5AR1 recombinant antibody, the EC 50 is 1.239-3.760 ng/mL.
Description
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. C5AR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 41.1 kDa and the accession number is P21730.
Species
Human
Expression System
HEK293 Cells
TagC-10xHis (This tag can be tested only under denaturing conditions)
Accession NumberP21730
Amino AcidMDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
Construction1-350 aa
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationPBS, pH 7.4, 6% trehalose
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsCD88, C5R1, C5AR1, C5AR, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor (C5a-R;C5aR)
Research Background
Chemical Properties
Molecular Weight41.1 kDa (predicted)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: C5AR1 Protein-VLP, Human, Recombinant (His) chemical structure | C5AR1 Protein-VLP, Human, Recombinant (His) molecular weight