CD123 Protein, Cynomolgus, Recombinant (His)

Name: CD123 Protein, Cynomolgus, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00639
Rating: 4.5 (1 reviews)

(Synonyms: Interleukin-3 receptor subunit α, Interleukin-3 receptor subunit alpha, IL-3R-α, IL-3R-alpha, IL-3RA, IL-3R subunit α, IL-3R subunit alpha, IL-3 receptor subunit α, IL-3 receptor subunit alpha) Copy Product Info

Synonyms: Interleukin-3 receptor subunit α, Interleukin-3 receptor subunit alpha, IL-3R-α, IL-3R-alpha, IL-3RA, IL-3R subunit α, IL-3R subunit alpha, IL-3 receptor subunit α, IL-3 receptor subunit alpha

Catalog No. TMPJ-00639 Copy Product Info

CD123 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is G8F3K3.

Pack Size	Price	USA Stock	Global Stock
5 µg	$55	35 days	35 days
10 µg	$86	35 days	35 days
20 µg	$137	35 days	35 days
50 µg	$262	35 days	35 days
100 µg	$488	35 days	35 days
200 µg	$923	35 days	35 days
500 µg	$2,150	35 days	35 days
1 mg	$3,220	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CD123 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is G8F3K3.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	G8F3K3
Amino Acid	Arg18-Arg302
Construction	Arg18-Arg302
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Interleukin-3 receptor subunit α, Interleukin-3 receptor subunit alpha, IL-3R-α, IL-3R-alpha, IL-3RA, IL-3R subunit α, IL-3R subunit alpha, IL-3 receptor subunit α, IL-3 receptor subunit alpha
Research Background	CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors. CD123 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage‑committed cells. CD123 is a heterodimer consisting of an alpha and a beta subunit. The alpha subunit alone binds IL‑3 with low affinity. The beta subunit does not bind IL‑3 by itself but is required for the high‑affinity binding of IL‑3 to the heterodimeric receptor complex.

Chemical Properties

Molecular Weight

50-65 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.