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Anti-SAP/SH2D1A Antibody (6R240)
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Catalog No. TMAY-01702
Alias XLPD1, XLPD, XLP, SH2 domain containing 1A, SAP/SH2D1A, SAP, MTCP1, LYP, IMD5, EBVS, DSHP
Anti-SAP/SH2D1A Antibody (6R240) is a Mouse antibody targeting SAP/SH2D1A. Anti-SAP/SH2D1A Antibody (6R240) can be used in ELISA(Cap).
Anti-SAP/SH2D1A Antibody (6R240)
Anti-SAP/SH2D1A Antibody (6R240)
😃Good
Catalog No. TMAY-01702Alias XLPD1, XLPD, XLP, SH2 domain containing 1A, SAP/SH2D1A, SAP, MTCP1, LYP, IMD5, EBVS, DSHP
Anti-SAP/SH2D1A Antibody (6R240) is a Mouse antibody targeting SAP/SH2D1A. Anti-SAP/SH2D1A Antibody (6R240) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SAP/SH2D1A Antibody (6R240) is a Mouse antibody targeting SAP/SH2D1A. Anti-SAP/SH2D1A Antibody (6R240) can be used in ELISA(Cap). |
| Alias | XLPD1, XLPD, XLP, SH2 domain containing 1A, SAP/SH2D1A, SAP, MTCP1, LYP, IMD5, EBVS, DSHP |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6R240 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SH2D1A ( NP_002342.1Pro2-Lys97). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of a catalytic domain and the presence of an SH2domain suggest that SH2D1A regulates one or more signal transduction pathways. SH2D1A interacts with signaling lymphocytic activation molecule (SLAM), which is a transmembrane protein expressed on the surface of activated T and B cells. SH2D1A (SAP) interacts via its SH2domain with a motif (TIYXXV) present in the cytoplasmic tail of the cell-surface receptors, including CD150 / SLAM, CD84, CD229 / Ly-9, and CD244 / 2B4. SH2D1A was expressed in EBV-carrying, tumor phenotype representative (type I), but not in EBV-carrying lymphoblastoid cell line (LCL)-like (type III) or EBV-negative Burkitt lymphoma (BL) lines. It has been supposed to be related to the X-linked lymphoproliferative disease which is also known as Duncan's disease or Purtilo syndrome. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human SH2D1A Protein (TMPY-02440) |
| Antigen Species | Human |
| Biology Area | Adaptor Proteins |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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