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Prosaptide Tx14(A) TFA is a prosaposin-derived peptide and a potent agonist of both GPR37L1 and GPR37, exhibiting EC50 values of 5 nM and 7 nM, respectively. In Schwann cells, this compound enhances phosphorylation of both ERK1 and ERK2 [1] [2].
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 5 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Prosaptide Tx14(A) TFA is a prosaposin-derived peptide and a potent agonist of both GPR37L1 and GPR37, exhibiting EC50 values of 5 nM and 7 nM, respectively. In Schwann cells, this compound enhances phosphorylation of both ERK1 and ERK2 [1] [2]. |
| In vitro | Prosaptide Tx14(A) TFA enhances GPR37 and GPR37L1 endocytosis, interacts with these receptors, and initiates signaling through a GPR37- and GPR37L1-dependent pathway. |
| Sequence | Thr-Ala-Leu-Ile-Asp-Asn-Asn-Ala-Thr-Glu-Glu-Ile-Leu-Tyr |
| Sequence Short | TALIDNNATEEILY |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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