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TargetMol | Compound Library

Orally Active Compound Library

Catalog No. L9850

Oral administration is the first choice for clinical drug delivery, especially for long-term use. It is also the safest, most convenient, and most economical method of drug delivery. Oral bioavailability is the percentage of the absorbed drug dose successfully passed through the mucosa of the gastrointestinal tract and entered the bloodstream through the liver, to the original given oral dose. Drugs with high oral bioavailability can achieve efficacy at lower doses and effectively reduce toxic side effects; while when bioavailability is too low, even compounds with good pharmacological activity are unable to be fully exposed and utilized at the target site, resulting in therapeutic failure or high dose with large toxic side effects, which eventually leads to drug development failure and limits the application.
TargetMol has carefully collected 3160 compounds with publicly reported oral activity that can be used for drug repurposing and development of orally active drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9850

Orally Active Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 3160 of orally active compounds for high-throughput screening and high-content screening.
  • Some drugs are approved or are in clinical trials with validated biological activity and safety.
  • Detailed specifications, compound structures, target information, activity descriptions, etc.
  • NMR and HPLC detection techniques to ensure high product purity.
  • All compounds are available in stock.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
Antibacterial
Antibiotic
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
Dopamine Receptor
Histamine Receptor
Parasite
COX
DNA/RNA Synthesis
AChR
HIV Protease
Potassium Channel
VEGFR
ROS
EGFR
Calcium Channel
Sodium Channel
Cytochromes P450
NF-κB
SARS-CoV
PDE
CDK
PDGFR
Dehydrogenase
p38 MAPK
Estrogen/progestogen Receptor
FLT
Reactive Oxygen Species
Glucocorticoid Receptor
c-Kit
Virus Protease
PI3K
Estrogen Receptor/ERR
RAAS
Akt
ERK
Antifungal
JAK
HCV Protease
Topoisomerase
Ferroptosis
Src
iGluR
Ras
Mitophagy
HBV
FGFR
Microtubule Associated
PPAR
Serotonin Transporter
Interleukin
Influenza Virus
c-Met/HGFR
GABA Receptor
HDAC
Proteasome
Reverse Transcriptase
Prostaglandin Receptor
TNF
TRP/TRPV Channel
mTOR
Bcr-Abl
GluR
Caspase
GPCR
Phosphatase
Androgen Receptor
Raf
Beta Amyloid
STAT
Epigenetic Reader Domain
Nucleoside Antimetabolite/Analog
HSV
MMP
MAPK
Norepinephrine
Histone Methyltransferase
ALK
LPL Receptor
Tyrosine Kinases
Cholinesterase (ChE)
Adenosine Receptor
Progesterone Receptor
Transferase
Mitochondrial Metabolism
P-gp
NO Synthase
Monoamine Oxidase
Angiotensin-converting Enzyme (ACE)
HIF/HIF Prolyl-Hydroxylase
GSK-3
PARP
MEK
Wnt/beta-catenin
Integrin
HSP
Bcl-2 Family
Antiviral
Thrombin
DPP-4
c-Fms
Opioid Receptor
Kras
ribosome
HER
Trk receptor
S1P Receptor
Proton pump
Drug Metabolite
NMDAR
Reductase
JNK
AMPK
TLR
Retinoid Receptor
Factor Xa
ROCK
Carbonic Anhydrase
Syk
Phospholipase
c-RET
Leukotriene Receptor
ROS Kinase
PKC
IGF-1R
Endothelin Receptor
TGF-beta/Smad
Acyltransferase
TAM Receptor
Aurora Kinase
MAO
Lipoxygenase
MDM-2/p53
NADPH
SGLT
ATPase
CCR
Serine Protease
Gamma-secretase
ATM/ATR
Glutathione Peroxidase
CXCR
Cannabinoid Receptor
MRP
Anti-infection
E1/E2/E3 Enzyme
IL Receptor
RSV
Thyroid hormone receptor(THR)
DHFR
PKA
Nrf2
Fatty Acid Synthase
Isocitrate Dehydrogenase (IDH)
Molecular Glues
PERK
CFTR
Complement System
CSF-1R
DNA gyrase
Antifection
HMG-CoA Reductase
IRAK
BTK
Histone Demethylase
ROR
Glucagon Receptor
Hedgehog/Smoothened
Neurokinin receptor
Serine/threonin kinase
Guanylate cyclase
Xanthine Oxidase
P2X Receptor
Ligands for E3 Ligase
CaMK
NOD-like Receptor (NLR)
Antioxidant
ABC Transporter
Casein Kinase
Hydroxylase
PLK
Beta-Secretase
IκB/IKK
DNA Alkylator/Crosslinker
Cysteine Protease
FXR
FAK
Vasopressin Receptor
IDO
Stearoyl-CoA Desaturase (SCD)
transporter
DNA Methyltransferase
LTR
glycosidase
P2Y Receptor
Chk
Antifolate
OX Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Aromatase
GHSR
HIF
PD-1/PD-L1
YAP
Pim
PROTACs
IAP
Sigma receptor
Amino Acids and Derivatives
Lipase
Smo
DNA Alkylation
Aryl Hydrocarbon Receptor
OXPHOS
Aminopeptidase
ASK
GNRH Receptor
Ephrin Receptor
PAI-1
ADC Cytotoxin
IKZF
IFNAR
BACE
Telomerase
Porcupine
DNA-PK
LDLR
Glucosidase
NOS
Melatonin Receptor
MAGL
NADPH-oxidase
p53
CRM1
RIP kinase
Thrombopoietin Receptor
PGE Synthase
Mdm2
PAK
Histone Acetyltransferase
MT Receptor
Neuropeptide Y Receptor
S6 Kinase
AhR
Vitamin
Monoamine Transporter
FAAH
DNA
Sirtuin
DUB
Cholecystokinin Receptor
FLAP
Neprilysin
Monocarboxylate transporter
MTP
UGT
GlyT
Protease-activated Receptor
GST
Oxytocin Receptor
Necroptosis
Annexin A
LPA Receptor
SGK
MicroRNA
Glucokinase
PAFR
Hexokinase
OAT
PI4K
Tie-2
TOPK
FOXO
Bradykinin Receptor
Epoxide Hydrolase
Free radical scavengers
Acetyl-CoA Carboxylase
FKBP
CGRP Receptor
MLK
Glutaminase
PAD
BCRP
Survivin
Discoidin Domain Receptor (DDR)
c-Myc
CaSR
NOD
Advanced Glycation End Products
Cell wall
OCT
Hck
Na-K-Cl cotransporter
Lipid
PDK
BMI-1
NEDD8
ATG
NR4A
PROTAC Linker
ATP Citrate Lyase
Hippo pathway
Imidazoline Receptor
Ligands for Target Protein for PROTAC
Galectin
Immunology/Inflammation related
MNK
GPCR19
Melanin-concentrating Hormone Receptor (MCHR)
SIK
Integrase
Adenosine Deaminase
MALT
IRE1
LDL
STING
LRRK2
GluCls
Tyrosinase
Neurotensin Receptor
Mucin
Wee1
Cuproptosis
Kinesin
Rho
Liver X Receptor
Melanocortin Receptor
Gap Junction Protein
Platelet aggregation
GRK
AAK1 (AP2 associated kinase 1)
Arp2/3 Complex
ACK1
Hydrogenase
CD38
Adiponectin Receptor
E3 Ligase Ligand-Linker Conjugates
p62
CRISPR/Cas9
Haspin Kinase
HCAR
Taste receptor
NPC1L1
AAK1
Myosin
Glutathione reductase
Decarboxylase
Chloride channel
Prolyl Endopeptidase (PREP)
PACAP
PTEN
Pyroptosis
GPX
RXFP receptor
PKM
ASBT
MIF
PYK2
Somatostatin
Urea Transporter
Methionine Adenosyltransferase (MAT)
DAPK
p97
GSNOR
Arginase
Na+/Ca2+ Exchanger
DYRK
GTPase
NAMPT
HCN Channel
cAMP
Sodium-dependent phosphate transporter
Ferroportin
PGC-1α

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