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TargetMol | Compound Library

Orally Active Compound Library

Catalog No. L9850

Oral administration is the first choice for clinical drug delivery, especially for long-term use. It is also the safest, most convenient, and most economical method of drug delivery. Oral bioavailability is the percentage of the absorbed drug dose successfully passed through the mucosa of the gastrointestinal tract and entered the bloodstream through the liver, to the original given oral dose. Drugs with high oral bioavailability can achieve efficacy at lower doses and effectively reduce toxic side effects; while when bioavailability is too low, even compounds with good pharmacological activity are unable to be fully exposed and utilized at the target site, resulting in therapeutic failure or high dose with large toxic side effects, which eventually leads to drug development failure and limits the application.
TargetMol has carefully collected 3160 compounds with publicly reported oral activity that can be used for drug repurposing and development of orally active drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9850

Orally Active Compound Library

sizeIn stock

  • 1 mg
  • 10 μL x 10 mM (in DMSO)
  • 20 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 3160 of orally active compounds for high-throughput screening and high-content screening.
  • Some drugs are approved or are in clinical trials with validated biological activity and safety.
  • Detailed specifications, compound structures, target information, activity descriptions, etc.
  • NMR and HPLC detection techniques to ensure high product purity.
  • All compounds are available in stock.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
Antibacterial
Antibiotic
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
Histamine Receptor
Dopamine Receptor
Parasite
COX
DNA/RNA Synthesis
AChR
HIV Protease
Potassium Channel
VEGFR
ROS
EGFR
Calcium Channel
Cytochromes P450
Sodium Channel
NF-κB
PDE
SARS-CoV
CDK
PDGFR
Dehydrogenase
Reactive Oxygen Species
Estrogen/progestogen Receptor
p38 MAPK
Glucocorticoid Receptor
FLT
c-Kit
PI3K
Virus Protease
Estrogen Receptor/ERR
RAAS
ERK
JAK
Akt
Antifungal
Ferroptosis
HCV Protease
Topoisomerase
Src
iGluR
Ras
HBV
FGFR
Microtubule Associated
Mitophagy
Serotonin Transporter
c-Met/HGFR
GABA Receptor
Influenza Virus
Interleukin
PPAR
Reverse Transcriptase
HDAC
Prostaglandin Receptor
TNF
mTOR
Proteasome
TRP/TRPV Channel
Bcr-Abl
GPCR
GluR
Caspase
Phosphatase
Beta Amyloid
Raf
STAT
Androgen Receptor
Epigenetic Reader Domain
Norepinephrine
ALK
Nucleoside Antimetabolite/Analog
HSV
Histone Methyltransferase
MMP
MAPK
LPL Receptor
NO Synthase
Adenosine Receptor
Progesterone Receptor
Tyrosine Kinases
Cholinesterase (ChE)
P-gp
Transferase
PARP
Mitochondrial Metabolism
Monoamine Oxidase
Integrin
GSK-3
Angiotensin-converting Enzyme (ACE)
HIF/HIF Prolyl-Hydroxylase
MEK
Bcl-2 Family
Wnt/beta-catenin
HSP
Antiviral
Trk receptor
c-Fms
Kras
Proton pump
Opioid Receptor
ribosome
HER
Drug Metabolite
JNK
DPP-4
S1P Receptor
TLR
Retinoid Receptor
Thrombin
Factor Xa
Reductase
AMPK
NMDAR
Leukotriene Receptor
ROCK
MDM-2/p53
ROS Kinase
Carbonic Anhydrase
Aurora Kinase
Phospholipase
c-RET
PKC
MAO
IGF-1R
Endothelin Receptor
TGF-beta/Smad
Acyltransferase
TAM Receptor
Syk
Glutathione Peroxidase
CXCR
Cannabinoid Receptor
SGLT
Lipoxygenase
ATPase
E1/E2/E3 Enzyme
CCR
MRP
ATM/ATR
Serine Protease
Gamma-secretase
Nrf2
NADPH
Anti-infection
Isocitrate Dehydrogenase (IDH)
Fatty Acid Synthase
Thyroid hormone receptor(THR)
DHFR
PKA
IL Receptor
RSV
DNA gyrase
Molecular Glues
IRAK
PERK
CFTR
P2X Receptor
Antifection
HMG-CoA Reductase
CSF-1R
Complement System
BTK
Serine/threonin kinase
Guanylate cyclase
Xanthine Oxidase
Antioxidant
Histone Demethylase
Ligands for E3 Ligase
Hedgehog/Smoothened
Neurokinin receptor
ROR
Glucagon Receptor
Cysteine Protease
FXR
CaMK
NOD-like Receptor (NLR)
Vasopressin Receptor
ABC Transporter
Casein Kinase
Hydroxylase
FAK
Beta-Secretase
IκB/IKK
PLK
DNA Alkylator/Crosslinker
IDO
Stearoyl-CoA Desaturase (SCD)
transporter
DNA Methyltransferase
Aromatase
GHSR
PD-1/PD-L1
LTR
glycosidase
Sigma receptor
Antifolate
OX Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Aminopeptidase
P2Y Receptor
Chk
Aryl Hydrocarbon Receptor
OXPHOS
YAP
Pim
Mdm2
GNRH Receptor
Ephrin Receptor
PAI-1
HIF
PROTACs
IAP
ASK
Smo
DNA Alkylation
Amino Acids and Derivatives
Lipase
ADC Cytotoxin
IKZF
NOS
Melatonin Receptor
MAGL
NADPH-oxidase
p53
IFNAR
BACE
Telomerase
PAK
Histone Acetyltransferase
Porcupine
CRM1
RIP kinase
Thrombopoietin Receptor
PGE Synthase
DNA-PK
LDLR
Glucosidase
Monocarboxylate transporter
MTP
MT Receptor
Neuropeptide Y Receptor
S6 Kinase
AhR
GST
Oxytocin Receptor
NOD
Vitamin
Monoamine Transporter
FAAH
DNA
UGT
GlyT
Protease-activated Receptor
Cholecystokinin Receptor
FLAP
Neprilysin
DUB
Bradykinin Receptor
Epoxide Hydrolase
Free radical scavengers
Acetyl-CoA Carboxylase
FKBP
CGRP Receptor
MLK
Necroptosis
Annexin A
LPA Receptor
SGK
c-Myc
CaSR
Sirtuin
Glutaminase
PAD
BCRP
Survivin
Discoidin Domain Receptor (DDR)
Tie-2
TOPK
FOXO
MicroRNA
Glucokinase
PAFR
Hexokinase
OAT
PI4K
MALT
IRE1
LDL
STING
LRRK2
GluCls
Tyrosinase
Advanced Glycation End Products
Cell wall
Hck
Na-K-Cl cotransporter
Lipid
PDK
BMI-1
Rho
Liver X Receptor
Melanocortin Receptor
Gap Junction Protein
Platelet aggregation
NEDD8
ATG
NR4A
PROTAC Linker
ATP Citrate Lyase
Hippo pathway
Imidazoline Receptor
Neurotensin Receptor
Mucin
Wee1
Cuproptosis
Kinesin
Melanin-concentrating Hormone Receptor (MCHR)
SIK
Integrase
Adenosine Deaminase
Ligands for Target Protein for PROTAC
Galectin
Immunology/Inflammation related
MNK
GPCR19
Chloride channel
Prolyl Endopeptidase (PREP)
PACAP
PTEN
Pyroptosis
GPX
RXFP receptor
PKM
OCT
GRK
AAK1 (AP2 associated kinase 1)
Arp2/3 Complex
ACK1
GSNOR
Arginase
Na+/Ca2+ Exchanger
DYRK
GTPase
NAMPT
HCN Channel
cAMP
Hydrogenase
CD38
Adiponectin Receptor
E3 Ligase Ligand-Linker Conjugates
p62
CRISPR/Cas9
ASBT
MIF
PYK2
Adenylate cyclase
Somatostatin
Urea Transporter
Methionine Adenosyltransferase (MAT)
DAPK
p97
Taste receptor
NPC1L1
AAK1
Myosin
Glutathione reductase
Decarboxylase
Haspin Kinase
HCAR
Sodium-dependent phosphate transporter
Ferroportin
PGC-1α

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