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TargetMol | Compound Library

Orally Active Compound Library

Catalog No. L9850

Oral administration is the first choice for clinical drug delivery, especially for long-term use. It is also the safest, most convenient, and most economical method of drug delivery. Oral bioavailability is the percentage of the absorbed drug dose successfully passed through the mucosa of the gastrointestinal tract and entered the bloodstream through the liver, to the original given oral dose. Drugs with high oral bioavailability can achieve efficacy at lower doses and effectively reduce toxic side effects; while when bioavailability is too low, even compounds with good pharmacological activity are unable to be fully exposed and utilized at the target site, resulting in therapeutic failure or high dose with large toxic side effects, which eventually leads to drug development failure and limits the application.
TargetMol has carefully collected 3160 compounds with publicly reported oral activity that can be used for drug repurposing and development of orally active drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9850

Orally Active Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 3160 of orally active compounds for high-throughput screening and high-content screening.
  • Some drugs are approved or are in clinical trials with validated biological activity and safety.
  • Detailed specifications, compound structures, target information, activity descriptions, etc.
  • NMR and HPLC detection techniques to ensure high product purity.
  • All compounds are available in stock.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
Antibacterial
Antibiotic
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
Histamine Receptor
Dopamine Receptor
Parasite
COX
AChR
DNA/RNA Synthesis
HIV Protease
Potassium Channel
VEGFR
ROS
EGFR
Calcium Channel
Sodium Channel
Cytochromes P450
NF-κB
PDE
SARS-CoV
CDK
PDGFR
Reactive Oxygen Species
Estrogen/progestogen Receptor
p38 MAPK
Dehydrogenase
FLT
Glucocorticoid Receptor
c-Kit
PI3K
Virus Protease
Estrogen Receptor/ERR
RAAS
Ferroptosis
ERK
JAK
Akt
Antifungal
HCV Protease
Topoisomerase
Ras
Src
iGluR
Serotonin Transporter
HBV
FGFR
Microtubule Associated
Mitophagy
PPAR
c-Met/HGFR
GABA Receptor
Influenza Virus
Interleukin
Reverse Transcriptase
BTK
TNF
Prostaglandin Receptor
mTOR
HDAC
Bcr-Abl
TRP/TRPV Channel
GPCR
GluR
Caspase
Phosphatase
Androgen Receptor
Beta Amyloid
MMP
Epigenetic Reader Domain
Raf
STAT
MAPK
ALK
Norepinephrine
Nucleoside Antimetabolite/Analog
HSV
Histone Methyltransferase
Cholinesterase (ChE)
LPL Receptor
Adenosine Receptor
Progesterone Receptor
NO Synthase
Tyrosine Kinases
Mitochondrial Metabolism
PARP
P-gp
Transferase
Angiotensin-converting Enzyme (ACE)
HIF/HIF Prolyl-Hydroxylase
Integrin
GSK-3
Monoamine Oxidase
DPP-4
Bcl-2 Family
Wnt/beta-catenin
HSP
MEK
Trk receptor
c-Fms
Antiviral
Kras
S1P Receptor
Proton pump
Opioid Receptor
ribosome
HER
Drug Metabolite
JNK
Thrombin
NMDAR
Factor Xa
TLR
Retinoid Receptor
Reductase
AMPK
MDM-2/p53
ROS Kinase
Leukotriene Receptor
Carbonic Anhydrase
Phospholipase
c-RET
ROCK
Syk
MAO
IGF-1R
Aurora Kinase
Endothelin Receptor
TGF-beta/Smad
Acyltransferase
TAM Receptor
PKC
Serine Protease
Gamma-secretase
Lipoxygenase
Glutathione Peroxidase
CXCR
Cannabinoid Receptor
ATPase
E1/E2/E3 Enzyme
CCR
MRP
ATM/ATR
SGLT
IL Receptor
RSV
Isocitrate Dehydrogenase (IDH)
Nrf2
Fatty Acid Synthase
Thyroid hormone receptor(THR)
DHFR
PKA
NADPH
Anti-infection
Complement System
IRAK
DNA gyrase
PERK
CFTR
P2X Receptor
Antifection
Proteasome
CSF-1R
Molecular Glues
ROR
Glucagon Receptor
Serine/threonin kinase
Guanylate cyclase
Xanthine Oxidase
Antioxidant
Histone Demethylase
Ligands for E3 Ligase
HMG-CoA Reductase
Hedgehog/Smoothened
Neurokinin receptor
PLK
Cysteine Protease
FXR
ABC Transporter
glycosidase
Casein Kinase
Hydroxylase
FAK
Beta-Secretase
IκB/IKK
CaMK
NOD-like Receptor (NLR)
P2Y Receptor
Chk
Vasopressin Receptor
Aromatase
GHSR
HIF
PD-1/PD-L1
DNA Alkylator/Crosslinker
LTR
Sigma receptor
Antifolate
Indoleamine 2,3-Dioxygenase (IDO)
Aminopeptidase
IDO
Stearoyl-CoA Desaturase (SCD)
transporter
DNA Methyltransferase
Amino Acids and Derivatives
Lipase
Mdm2
GNRH Receptor
Ephrin Receptor
PAI-1
MTP
Aryl Hydrocarbon Receptor
OXPHOS
PROTACs
IAP
OX Receptor
ASK
Glucosidase
Smo
DNA Alkylation
YAP
Pim
IKZF
ADC Cytotoxin
PAK
Histone Acetyltransferase
NOS
Melatonin Receptor
MAGL
NADPH-oxidase
p53
Porcupine
CRM1
RIP kinase
Thrombopoietin Receptor
PGE Synthase
DNA-PK
LDLR
BACE
IFNAR
Telomerase
DUB
GST
NOD
Monocarboxylate transporter
Vitamin
Monoamine Transporter
FAAH
DNA
UGT
GlyT
Protease-activated Receptor
Cholecystokinin Receptor
FLAP
Neprilysin
MT Receptor
Neuropeptide Y Receptor
S6 Kinase
AhR
MicroRNA
Glucokinase
PAFR
Hexokinase
OAT
PI4K
c-Myc
CaSR
Oxytocin Receptor
Bradykinin Receptor
Epoxide Hydrolase
Free radical scavengers
Acetyl-CoA Carboxylase
FKBP
CGRP Receptor
MLK
Sirtuin
Glutaminase
PAD
BCRP
Survivin
Discoidin Domain Receptor (DDR)
Tie-2
TOPK
FOXO
Necroptosis
Annexin A
LPA Receptor
SGK
Ligands for Target Protein for PROTAC
Galectin
Immunology/Inflammation related
PANoptosis
MNK
GPCR19
Rho
Liver X Receptor
Melanocortin Receptor
Dipeptidyl Peptidase
Gap Junction Protein
Platelet aggregation
MALT
IRE1
LDL
STING
LRRK2
GluCls
Tyrosinase
NEDD8
ATG
NR4A
PROTAC Linker
ATP Citrate Lyase
Hippo pathway
Imidazoline Receptor
Neurotensin Receptor
Mucin
Wee1
Cuproptosis
Kinesin
Melanin-concentrating Hormone Receptor (MCHR)
SIK
Integrase
Adenosine Deaminase
Advanced Glycation End Products
Cell wall
Hck
GRK
Na-K-Cl cotransporter
Lipid
PDK
BMI-1
Ferroportin
PGC-1α
Haspin Kinase
HCAR
Protease
GSNOR
Arginase
Na+/Ca2+ Exchanger
DYRK
GTPase
NAMPT
HCN Channel
cAMP
Chloride channel
Prolyl Endopeptidase (PREP)
PACAP
PTEN
Pyroptosis
GPX
RXFP receptor
PKM
Hydrogenase
CD38
Adiponectin Receptor
E3 Ligase Ligand-Linker Conjugates
p62
CRISPR/Cas9
ASBT
MIF
PYK2
Adenylate cyclase
Somatostatin
Urea Transporter
Methionine Adenosyltransferase (MAT)
DAPK
p97
Taste receptor
NPC1L1
AAK1
Myosin
Glutathione reductase
Decarboxylase
OCT
AAK1 (AP2 associated kinase 1)
Arp2/3 Complex
ACK1
Sodium-dependent phosphate transporter

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