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Anti-Phospho-Tau (Ser202, Thr205) Antibody (5E928)
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Catalog No. TMAY-01633
Alias Tau-PHF6, tau-40, TAU, PPP1R103, PPND, MTBT2, MTBT1, MSTD, MGC138549, MAPTL, FTDP-17, FLJ31424, DDPAC
Anti-Phospho-Tau (Ser202, Thr205) Antibody (5E928) is a Rabbit antibody targeting Phospho-Tau (Ser202, Thr205). Anti-Phospho-Tau (Ser202, Thr205) Antibody (5E928) can be used in WB.
Anti-Phospho-Tau (Ser202, Thr205) Antibody (5E928)
Anti-Phospho-Tau (Ser202, Thr205) Antibody (5E928)
😃Good
Catalog No. TMAY-01633Alias Tau-PHF6, tau-40, TAU, PPP1R103, PPND, MTBT2, MTBT1, MSTD, MGC138549, MAPTL, FTDP-17, FLJ31424, DDPAC
Anti-Phospho-Tau (Ser202, Thr205) Antibody (5E928) is a Rabbit antibody targeting Phospho-Tau (Ser202, Thr205). Anti-Phospho-Tau (Ser202, Thr205) Antibody (5E928) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $80 | 7-10 days | |
| 100 μL | $233 | 7-10 days |
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| Description | Anti-Phospho-Tau (Ser202, Thr205) Antibody (5E928) is a Rabbit antibody targeting Phospho-Tau (Ser202, Thr205). Anti-Phospho-Tau (Ser202, Thr205) Antibody (5E928) can be used in WB. |
| Alias | Tau-PHF6, tau-40, TAU, PPP1R103, PPND, MTBT2, MTBT1, MSTD, MGC138549, MAPTL, FTDP-17, FLJ31424, DDPAC |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 5E928 |
| Reactivity | Human;
Predicted to React with:Species predicted to react based on 100% sequence homology: Cynomolgus; Phospho-Tau (Ser202, Thr205) of P10636-8 in UniProt, which corresponds to Phospho-Tau (Ser519, Thr522) of P10636-1 in UniProt. |
| Verified Activity | 1. Western blot analysis of extracts from mouse brain (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-Tau (Ser202, Thr205) rabbit monoclonal Antibody at 1:2000 dilution. (Validation Experiment) 2. Western blot analysis of extracts from rat brain using Phospho-Tau (Ser202, Thr205) rabbit monoclonal Antibody at 1:5000 dilution. 3. Western blot analysis of 200 ng Recombinant Human Tau Protein (Full Length) (line A) and 200 ng Recombinant Human Tau Protein (Full Length), GSK3beta-phosphorylated (line B) using Phospho-Tau (Ser202, Thr205) Rabbit Monoclonal Antibody at 1:5000 dilution. |
| Application | WB |
| Recommended Dose | WB: 1:2000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around (Ser202, Thr205) of the Human Phospho-Tau. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Other nervous system MAPs may perform similar functions, as suggested by tau knockout mice, who did not show abnormalities in brain development - possibly because of compensation in tau deficiency by other MAPs. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic phosphopeptide corresponding to residues around (Ser202, Thr205) of the Human Phospho-Tau |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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