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Antidepressant Compound Library

Catalog No. L9860
  Library Compound List   Excel SDF

Depression is a common mental disorder, and according to the World Health Organization (WHO), more than 350 million people in the world are suffering from depression, and the number is growing rapidly. Depression is associated with a lack of concentration, depressed mood, slowed thinking, sleep disorders, changes in appetite and weight, as well as pessimistic and even suicidal thoughts. There are more than 800,000 people dying each year due to depression.

Medication is the main means of depression treatment. In recent decades, a series of antidepressants have been developed. However, existing antidepressants have certain limitations, such as lagging clinical effects or low response, as well as a series of potential side effects. Since the development of antidepressants is relatively slow compared to the many incidences of depression, it has been included by WHO as one of the most urgent drugs to be developed in the 21st century.

The TargetMol antidepressant compound library collects 1181 compounds related to depression, including compounds that have been reported to have therapeutic effects in depression, as well as compounds that target depression-related targets.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • 1181 compounds associated with depression that can be used for high-throughput and high-content screening;
  • Some of the compounds are marketed or have entered the clinical phase;
  • Detailed instructions, compound structure, target information, activity description, etc;
  • Multiple detection techniques such as NMR, HPLC/LCMS to ensure correct structure and high purity of the product and reduce false positives.

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L9860)

Publications Cited TargetMol Libraries

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Library Composition

NF-κB (185)
PI3K (169)
Apoptosis (156)
5-HT Receptor (141)
Autophagy (137)
mTOR (89)
Akt (87)
Dopamine Receptor (84)
NMDAR (70)
AMPK (66)
Endogenous Metabolite (61)
GSK-3 (55)
Reactive Oxygen Species (48)
iGluR (41)
GABA Receptor (41)
Adrenergic Receptor (40)
Antibacterial (38)
Monoamine Oxidase (38)
DNA-PK (37)
Serotonin Transporter (36)
ERK (31)
CDK (30)
COX (30)
S6 Kinase (29)
Norepinephrine (29)
MAO (27)
IκB/IKK (27)
p38 MAPK (26)
ATM/ATR (23)
AChR (23)
TNF (22)
GluR (21)
Parasite (21)
PDK (19)
JNK (19)
Histamine Receptor (19)
Potassium Channel (15)
Caspase (15)
P450 (15)
STAT (15)
Mitophagy (15)
HIV Protease (14)
PI4K (13)
Sodium Channel (13)
Influenza Virus (13)
Antifungal (12)
RIP kinase (12)
Calcium Channel (12)
IL Receptor (12)
PKC (11)
Antibiotic (11)
BCL (10)
NO Synthase (10)
PKA (10)
Src (10)
Ferroptosis (10)
MAPK (9)
NOD (9)
NOD-like Receptor (NLR) (9)
Opioid Receptor (9)
Antioxidant (9)
MEK (9)
DNA/RNA Synthesis (9)
PTEN (8)
Casein Kinase (8)
VEGFR (8)
p53 (7)
Lipoxygenase (7)
FLT (7)
Interleukin (7)
MMP (7)
Beta Amyloid (6)
Bcr-Abl (6)
Microtubule Associated (6)
NOS (6)
Dehydrogenase (6)
Chk (6)
PPAR (6)
SIK (6)
ROCK (6)
IRAK (6)
Chloride channel (5)
Histone Demethylase (5)
HDAC (5)
IGF-1R (5)
JAK (5)
PARP (5)
Topoisomerase (5)
HSV (5)
Aurora Kinase (5)
Antiviral (5)
E1/E2/E3 Enzyme (5)
MELK (5)
Mitochondrial Metabolism (5)
ROS (5)
AChE (4)
CaMK (4)
Nrf2 (4)
Epigenetic Reader Domain (4)
Carbonic Anhydrase (4)
Proteasome (4)
Virus Protease (4)
Aryl Hydrocarbon Receptor (4)
Phosphatase (4)
PDGFR (4)
PDE (4)
FAK (4)
Wnt/beta-catenin (4)
TLR (4)
EGFR (3)
SGK (3)
Glucosidase (3)
Melatonin Receptor (3)
FGFR (3)
Prostaglandin Receptor (3)
PGE Synthase (3)
MT Receptor (3)
P-gp (3)
Sigma receptor (3)
Tyrosinase (3)
Raf (3)
ATPase (3)
Amino Acids and Derivatives (3)
transporter (3)
HIF/HIF Prolyl-Hydroxylase (3)
HIF (3)
PLK (3)
Transferase (3)
Integrin (3)
TRP/TRPV Channel (3)
HCV Protease (3)
TGF-beta/Smad (3)
RAAS (3)
OX Receptor (2)
Adenosine Receptor (2)
Neuropeptide Y Receptor (2)
BACE (2)
Androgen Receptor (2)
c-RET (2)
MRP (2)
Leukotriene Receptor (2)
Rho (2)
Cannabinoid Receptor (2)
HSP (2)
IAP (2)
Anti-infection (2)
Imidazoline Receptor (2)
Guanylate cyclase (2)
HER (2)
GPR (2)
Trk receptor (2)
Tyrosine Kinases (2)
Serine Protease (2)
SARS-CoV (2)
Gamma-secretase (2)
FAAH (2)
Estrogen/progestogen Receptor (2)
Estrogen Receptor/ERR (2)
Drug Metabolite (2)
BCRP (1)
CCR (1)
Tie-2 (1)
PKM (1)
STING (1)
Telomerase (1)
Syk (1)
RSV (1)
Beta-Secretase (1)
Sirtuin (1)
c-Fms (1)
Serine/threonin kinase (1)
RANKL/RANK (1)
Adenosine deaminase (1)
S1P Receptor (1)
Reductase (1)
Reverse Transcriptase (1)
Pim (1)
NADPH-oxidase (1)
AhR (1)
Hck (1)
Liver X Receptor (1)
Kinesin (1)
DNA (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
Immunology/Inflammation related (1)
IFNAR (1)
HMG-CoA Reductase (1)
ATP Citrate Lyase (1)
Histone Methyltransferase (1)
Hedgehog/Smoothened (1)
HBV (1)
LRRK2 (1)
GTPase (1)
GST (1)
DUB (1)
GRK (1)
GlyT (1)
Glutathione Peroxidase (1)
DYRK (1)
Glucokinase (1)
Glucocorticoid Receptor (1)
FXR (1)
Fatty Acid Synthase (1)
LPA Receptor (1)
LTR (1)
Phospholipase (1)
c-Myc (1)
PERK (1)
PAK (1)
cholecystokinin (1)
c-Kit (1)
P2X Receptor (1)
Oxytocin Receptor (1)
ALK (1)
c-Met/HGFR (1)
OCT (1)
NPC1L1 (1)
Aminopeptidase (1)
lysosomal autophagy (1)
NADPH (1)
Myosin (1)
CRFR (1)
Monocarboxylate transporter (1)
Monoamine Transporter (1)
Antifection (1)
MLK (1)
CRISPR/Cas9 (1)
Melanin-concentrating Hormone Receptor (MCHR) (1)
Mdm2 (1)
DAPK (1)
YAP (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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