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Anti-CTSS/Cathepsin S Antibody (Fsn0503h)

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Catalog No. T9901A-606 Copy Product Info
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Anti-CTSS/Cathepsin S Antibody (Fsn0503h) is a humanized monoclonal antibody targeting CTSS/Cathepsin S. It reduces the invasive capacity of cell lines expressing Cathepsin S in vitro and exhibits antitumor effects both in vitro and in vivo.
Anti-CTSS/Cathepsin S Antibody (Fsn0503h)
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$745-In Stock
10 mg$1,180-In Stock
25 mg$1,770-In Stock
50 mg$2,380-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:98.2% (SDS-PAGE); 97.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-CTSS/Cathepsin S Antibody (Fsn0503h) is a humanized monoclonal antibody targeting CTSS/Cathepsin S. It reduces the invasive capacity of cell lines expressing Cathepsin S in vitro and exhibits antitumor effects both in vitro and in vivo.
In vitro
Anti-CTSS/Cathepsin S Antibody (Fsn0503h) (1–1000 nM; 24 h) concentration-dependently inhibited Matrigel invasion in four Cat-S-expressing cell lines: MDA-MB-361, CaKi-1, CaKi-2, and U87MG.
In vivo
Anti-CTSS/Cathepsin S Antibody (Fsn0503h) (10-20 mg/kg; intravenous injection; three times weekly) exhibits antitumor activity in a Colo-205 colorectal cancer xenograft mouse model. Although the 10 mg/kg dose demonstrated superior T/C% values compared to the 20 mg/kg dose, no significant difference in tumor reduction was observed between the two doses [1].
Clone
Fsn0503h
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetCTSS/CathepsinS
Chemical Properties
Molecular Weight145.16 kDa
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Related Tags: Anti-CTSS/Cathepsin S Antibody (Fsn0503h) chemical structure | Anti-CTSS/Cathepsin S Antibody (Fsn0503h) in vivo | Anti-CTSS/Cathepsin S Antibody (Fsn0503h) in vitro | Anti-CTSS/Cathepsin S Antibody (Fsn0503h) molecular weight