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Anti-CTSS/Cathepsin S Antibody (Fsn0503h)
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Catalog No. T9901A-606
Anti-CTSS/Cathepsin S Antibody (Fsn0503h) is a humanized monoclonal antibody targeting CTSS/Cathepsin S. It reduces the invasive capacity of cell lines expressing Cathepsin S in vitro and exhibits antitumor effects both in vitro and in vivo.
Anti-CTSS/Cathepsin S Antibody (Fsn0503h)
Anti-CTSS/Cathepsin S Antibody (Fsn0503h)
Copy Product Info😃Good
Catalog No. T9901A-606
Anti-CTSS/Cathepsin S Antibody (Fsn0503h) is a humanized monoclonal antibody targeting CTSS/Cathepsin S. It reduces the invasive capacity of cell lines expressing Cathepsin S in vitro and exhibits antitumor effects both in vitro and in vivo.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $745 | - | In Stock | |
| 10 mg | $1,180 | - | In Stock | |
| 25 mg | $1,770 | - | In Stock | |
| 50 mg | $2,380 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.2% (SDS-PAGE); 97.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Anti-CTSS/Cathepsin S Antibody (Fsn0503h) is a humanized monoclonal antibody targeting CTSS/Cathepsin S. It reduces the invasive capacity of cell lines expressing Cathepsin S in vitro and exhibits antitumor effects both in vitro and in vivo. |
| In vitro | Anti-CTSS/Cathepsin S Antibody (Fsn0503h) (1–1000 nM; 24 h) concentration-dependently inhibited Matrigel invasion in four Cat-S-expressing cell lines: MDA-MB-361, CaKi-1, CaKi-2, and U87MG. |
| In vivo | Anti-CTSS/Cathepsin S Antibody (Fsn0503h) (10-20 mg/kg; intravenous injection; three times weekly) exhibits antitumor activity in a Colo-205 colorectal cancer xenograft mouse model. Although the 10 mg/kg dose demonstrated superior T/C% values compared to the 20 mg/kg dose, no significant difference in tumor reduction was observed between the two doses [1]. |
| Clone | Fsn0503h |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CTSS/CathepsinS |
| Molecular Weight | 145.16 kDa |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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