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Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody

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Catalog No. TMAC-03500

Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RAD17 (Ser635). Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody can be used in WB.

Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody

Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody

😃Good
Catalog No. TMAC-03500
Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RAD17 (Ser635). Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2177-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RAD17 (Ser635). Anti-Phospho-RAD17 (Ser635) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research BackgroundRAD17 checkpoint clamp loader component(RAD17) Homo sapiens The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, h
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human Rad17 around the phosphorylation site of Ser635
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 77 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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