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Anti-Phospho-Integrin b3 (Tyr785) Polyclonal Antibody (Synonyms: p-Integrin b3 (Y785), p-Integrin b3 (Tyr785)||...)
Catalog No. TMAC-02179 Copy Product Info
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Anti-Phospho-Integrin b3 (Tyr785) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Integrin b3 (Tyr785). Anti-Phospho-Integrin b3 (Tyr785) Polyclonal Antibody can be used in WB.
Anti-Phospho-Integrin b3 (Tyr785) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAC-02179
Synonyms p-Integrin b3 (Y785), p-Integrin b3 (Tyr785), Integrin b3 (p-Y785), Integrin b3 (p-Tyr785)
Anti-Phospho-Integrin b3 (Tyr785) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Integrin b3 (Tyr785). Anti-Phospho-Integrin b3 (Tyr785) Polyclonal Antibody can be used in WB.
Anti-Phospho-Integrin b3
(Tyr785) Polyclonal Antibody
(Tyr785) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $216 | 7-10 days | 7-10 days | |
| 100 μL | $318 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
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Chemical Properties
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| Description | Anti-Phospho-Integrin b3 (Tyr785) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Integrin b3 (Tyr785). Anti-Phospho-Integrin b3 (Tyr785) Polyclonal Antibody can be used in WB. |
| Synonyms | p-Integrin b3 (Y785), p-Integrin b3 (Tyr785), Integrin b3 (p-Y785), Integrin b3 (p-Tyr785) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from HUVEC cells using Integrin b3 (Phospho-Tyr785) Antibody TMAC-02179 and the same antibody preincubated with blocking peptide .  |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Integrin a-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin a-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins a-IIb/beta-3 and a-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin a-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin a-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 785 (I-T-Y(p)-R-G) derived from Human Integrin b3 |
| Antigen Species | human |
| Uniprot ID |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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