IGF1/IGF-I Protein, Salmon, Recombinant

Name: IGF1/IGF-I Protein, Salmon, Recombinant
Brand: TargetMol
SKU: TMPS-00055
Rating: 4.5 (1 reviews)

(Synonyms: Somatomedin, Insulin-like growth factor I, IGF-1, IGF1) Copy Product Info

Synonyms: Somatomedin, Insulin-like growth factor I, IGF-1, IGF1

Catalog No. TMPS-00055 Copy Product Info

IGF1/IGF-I Protein, Salmon, Recombinant is expressed in E. coli. The accession number is Q02815.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$97	7-10 days	7-10 days
10 µg	$158	7-10 days	7-10 days
20 µg	$233	7-10 days	7-10 days
50 µg	$393	7-10 days	7-10 days
100 µg	$588	7-10 days	7-10 days
200 µg	$943	7-10 days	7-10 days
500 µg	$1,760	7-10 days	7-10 days
1 mg	$2,850	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 15.0 ng/ml as determined by a dose-response proliferation assay using FDC-P1 cells. Based on the ED 50 , the calculated specific activity is approximately >6.7 × 10 4 units/mg. It is recommended to experimentally determine the optimal concentration for each specific application by performing a dose response assay.
Description	IGF1/IGF-I Protein, Salmon, Recombinant is expressed in E. coli. The accession number is Q02815.
Species	Salmon
Expression System	E. coli
Tag	Tag Free
Accession Number	Q02815
Construction	Gly45-Ala114
Protein Purity	≥ 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Somatomedin, Insulin-like growth factor I, IGF-1, IGF1
Research Background	Insulin-like growth factor 1 (IGF-1), also called Somatomedin, is a hormone similar in molecular structure to insulin but has a much higher growth-promoting activity. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. It is able to stimulate glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. It may also play a role in synapse maturation.

Chemical Properties

Molecular Weight

7.7 kDa (Predicted); 8.0 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, the lyophilized product remains stable for up to 6 months at lower than -70 °C. Upon reconstitution, the product is stable for up to 1 week at 4 °C or up to 3 months at -20 °C. Avoid repeated freeze-thaw cycles by making single-use aliquots before the solution is stored at -20 °C.