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DSG-2/Desmoglein-2 Protein, Human, Recombinant (His)
(Synonyms: MGC117037, MGC117036, HDGC, DSG2, Desmoglein-2, CMD1BB, CDHF5, ARVC10) Copy Product InfoSynonyms: MGC117037, MGC117036, HDGC, DSG2, Desmoglein-2, CMD1BB, CDHF5, ARVC10
Catalog No. TMPK-00967 Copy Product Info
Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions. DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 63.6 kDa and the accession number is Q14126.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $51 | - | In Stock | |
| 10 µg | $80 | - | In Stock | |
| 20 µg | $129 | 7-10 days | 7-10 days | |
| 50 µg | $248 | 7-10 days | 7-10 days | |
| 100 µg | $418 | - | In Stock | |
| 200 µg | $757 | 7-10 days | 7-10 days | |
| 500 µg | $1,670 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Bis-Tris PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human DSG-2, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 10.7ng/ml determined by ELISA. |
| Description | Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions. DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 63.6 kDa and the accession number is Q14126. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q14126 |
| Construction | Ala50-Gly609 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | MGC117037, MGC117036, HDGC, DSG2, Desmoglein-2, CMD1BB, CDHF5, ARVC10 |
| Research Background | Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions. |
| Molecular Weight | 63.6 kDa (predicted). Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) chemical structure | DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) molecular weight
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