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CHAPS

Name: CHAPS
Brand: TargetMol
SKU: T19235
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19235Cas No. 75621-03-3

CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins.

CHAPS

🥰Excellent

Purity: 99.75%

Catalog No. T19235Cas No. 75621-03-3

CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins.

Pack Size	Price	Availability	Quantity
500 mg	$41	In Stock

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Purity:99.75%

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Product Introduction

Bioactivity

Description	CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins.
In vitro	CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions, and is electrically neutral. CHAPS is also useful in ion-exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. The critical micelle concentration of CHAPS is 6-10mM.

Chemical Properties

Molecular Weight	614.88
Formula	C₃₂H₅₈N₂O₇S
Cas No.	75621-03-3
Smiles	O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(NCCC[N+](CCCS(=O)(=O)[O-])(C)C)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]
Relative Density.	1.01 g/mL at 20°C
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 46 mg/mL (74.81 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.6263 mL	8.1317 mL	16.2633 mL	81.3167 mL
5 mM	0.3253 mL	1.6263 mL	3.2527 mL	16.2633 mL
10 mM	0.1626 mL	0.8132 mL	1.6263 mL	8.1317 mL
20 mM	0.0813 mL	0.4066 mL	0.8132 mL	4.0658 mL
50 mM	0.0325 mL	0.1626 mL	0.3253 mL	1.6263 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc