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Anti-P311 Polyclonal Antibody
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Catalog No. TMAB-01317
Alias PTZ17, Protein p311, PRO1873, P311 protein, NREP, Neuronal regeneration-related protein, Neuronal protein 3.1, D4S114, Chromosome 5 open reading frame 13, C5orf13
Anti-P311 Polyclonal Antibody is a Rabbit antibody targeting P311. Anti-P311 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Anti-P311 Polyclonal Antibody
Anti-P311 Polyclonal Antibody
😃Good
Catalog No. TMAB-01317Alias PTZ17, Protein p311, PRO1873, P311 protein, NREP, Neuronal regeneration-related protein, Neuronal protein 3.1, D4S114, Chromosome 5 open reading frame 13, C5orf13
Anti-P311 Polyclonal Antibody is a Rabbit antibody targeting P311. Anti-P311 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-P311 Polyclonal Antibody is a Rabbit antibody targeting P311. Anti-P311 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA. |
| Synonyms | PTZ17, Protein p311, PRO1873, P311 protein, NREP, Neuronal regeneration-related protein, Neuronal protein 3.1, D4S114, Chromosome 5 open reading frame 13, C5orf13 |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Expressed in lung (at protein level). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | P311, also called PTZ17, was identified by suppressive subtraction hybridization as potentially involved in smooth muscle (SM) myogenesis., an 8-kDa polypeptide, was previously shown to be highly expressed in invasive glioma cells. P311 is constitutively serine-phosphorylated; decreased phosphorylation is observed in migration-activated glioma cells. The primary amino acid sequence of P311 indicates a putative serine phosphorylation site (S59) near the PEST domain. Site-directed mutagenesis of S59A retarded P311 degradation and induced glioma cell motility. In contrast, S59D mutation resulted in the rapid degradation of P311 and reduced glioma cell migration. |
| Immunogen | KLH conjugated synthetic peptide: human P311 |
| Antigen Species | Human |
| Gene Name | NREP |
| Gene ID | |
| Protein Name | Neuronal regeneration-related protein |
| Uniprot ID | |
| Biology Area | Lipid Droplet Protein,Cell differentiation,Neuroregeneration,Lipid metabolism |
| Function | May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3 (By similarity). May play a role in the regulation of alveolar generation. |
| Molecular Weight | Theoretical: 7.9 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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