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Anti-LAMP1 Polyclonal Antibody
(Synonyms: lysosomal-associated membrane protein 1) Copy Product Info
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Synonyms: lysosomal-associated membrane protein 1
Catalog No. TMAB-01046 Copy Product Info
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Anti-LAMP1 Polyclonal Antibody is a Rabbit antibody targeting LAMP1. Anti-LAMP1 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-LAMP1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-LAMP1 Polyclonal Antibody is a Rabbit antibody targeting LAMP1. Anti-LAMP1 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | lysosomal-associated membrane protein 1 |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM=2 μg/Test; ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation. |
| Immunogen | KLH conjugated synthetic peptide: human LAMP-1 |
| Antigen Species | Human |
| Gene Name | LAMP1 |
| Gene ID | |
| Protein Name | Lysosome-associated membrane glycoprotein 1 |
| Uniprot ID | |
| Biology Area | Signal Transduction,Autophagy,Autophagy and mitophagy,SARS Coronavirus,Growth Cone,Soma marker,Neurogenesis,lamp1,Organelle Proteins,B Lymphocytic Lineage,T Lymphocytic Lineage,Monocytic Lineage,Lysosome |
| Function | Presents carbohydrate ligands to selectins. Also mplicated in tumor cell metastasis. |
| Molecular Weight | Theoretical: 42 kDa. Actual: 95 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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