B7-2/CD86 Protein, Cynomolgus, Recombinant (hFc)

Name: B7-2/CD86 Protein, Cynomolgus, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-00632
Rating: 4.5 (1 reviews)

(Synonyms: T-lymphocyte activation antigen CD86 isoform 1, CD86, Activation B7-2 antigen) Copy Product Info

Synonyms: T-lymphocyte activation antigen CD86 isoform 1, CD86, Activation B7-2 antigen

Catalog No. TMPJ-00632 Copy Product Info

B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession number is G7NXR4.

B7-2/CD86 Protein, Cynomolgus, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
5 µg	$44	7-10 days	7-10 days
10 µg	$68	7-10 days	7-10 days
20 µg	$109	7-10 days	7-10 days
50 µg	$211	7-10 days	7-10 days
100 µg	$393	7-10 days	7-10 days
200 µg	$742	7-10 days	7-10 days
500 µg	$1,730	7-10 days	7-10 days
1 mg	$2,480	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession number is G7NXR4.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	G7NXR4
Amino Acid	Ala19-His240
Construction	Ala19-His240
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	T-lymphocyte activation antigen CD86 isoform 1, CD86, Activation B7-2 antigen
Research Background	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.

Chemical Properties

Molecular Weight

70-100 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.