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Ampreloxetine hydrochloride

Name: Ampreloxetine hydrochloride
Brand: TargetMol
SKU: T67937
Price: 80 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T67937Cas No. 1227056-87-2

Alias TD-9855 HCl

Ampreloxetine hydrochloride (TD-9855 HCl) has anti-inflammatory activity and is a potential compound for the treatment of depression and Alzheimer's disease.

Ampreloxetine hydrochloride

🥰Excellent

Purity: 99.90%

Catalog No. T67937Alias TD-9855 HClCas No. 1227056-87-2

Ampreloxetine hydrochloride (TD-9855 HCl) has anti-inflammatory activity and is a potential compound for the treatment of depression and Alzheimer's disease.

Pack Size	Price	Availability
1 mg	$80	In Stock
5 mg	$197	In Stock
10 mg	$322	In Stock
25 mg	$547	In Stock
50 mg	$788	In Stock
100 mg	$1,080	In Stock
500 mg	$2,180	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.90%

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COA FNMR IC HNMR LCMS

Product Introduction

Bioactivity

Description	Ampreloxetine hydrochloride (TD-9855 HCl) has anti-inflammatory activity and is a potential compound for the treatment of depression and Alzheimer's disease.
Targets&IC50	rat Serotonin transporter:8.9 (pIC50), Norepinephrine transporter (rat):7.9 (pIC50), Norepinephrine transporter (human):8.0 (pIC50), Serotonin transporter (human):8.6 (pIC50)
Synonyms	TD-9855 HCl

Chemical Properties

Molecular Weight	357.8
Formula	C₁₈H₁₉ClF₃NO
Cas No.	1227056-87-2
Smiles	Cl.FC=1C=C(F)C(OCC=2C=CC=CC2C3CCNCC3)=C(F)C1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (139.74 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7949 mL	13.9743 mL	27.9486 mL	139.7429 mL
5 mM	0.5590 mL	2.7949 mL	5.5897 mL	27.9486 mL
10 mM	0.2795 mL	1.3974 mL	2.7949 mL	13.9743 mL
20 mM	0.1397 mL	0.6987 mL	1.3974 mL	6.9871 mL
50 mM	0.0559 mL	0.2795 mL	0.5590 mL	2.7949 mL
100 mM	0.0279 mL	0.1397 mL	0.2795 mL	1.3974 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc