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PIN4 Protein, Human, Recombinant (His)

Catalog No. TMPJ-01396
Synonyms: Peptidyl-prolyl cis-trans isomerase Pin4, Parvulin-14, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Rotamase Pin4, PIN4, Peptidyl-prolyl cis/trans isomerase EPVH, Parvulin-17

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.

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PIN4 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 116.00
50 μg 5 days $ 352.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.
Species Human
Expression System E. coli
Tag N-6His
Accession Number Q9Y237-2
Synonyms Peptidyl-prolyl cis-trans isomerase Pin4, Parvulin-14, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Rotamase Pin4, PIN4, Peptidyl-prolyl cis/trans isomerase EPVH, Parvulin-17
Amino Acid Met1-Lys156
Construction Recombinant Human Parvulin-14 is produced by our E.coli expression system and the target gene encoding Met1-Lys156 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 21 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.5.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.

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Keywords

PIN4 Protein, Human, Recombinant (His) Peptidyl-prolyl cis-trans isomerase Pin4 Parvulin-14 PIN 4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 Rotamase Pin4 PIN4 Peptidyl-prolyl cis/trans isomerase EPVH Parvulin-17 PIN-4 recombinant recombinant-proteins proteins protein

 

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