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PIN4 Protein, Human, Recombinant (His)

(Synonyms: Rotamase Pin4, PIN4, Peptidyl-prolyl cis-trans isomerase Pin4, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Peptidyl-prolyl cis/trans isomerase EPVH, Parvulin-17, Parvulin-14) Copy Product Info

Synonyms: Rotamase Pin4, PIN4, Peptidyl-prolyl cis-trans isomerase Pin4, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Peptidyl-prolyl cis/trans isomerase EPVH, Parvulin-17, Parvulin-14

Catalog No. TMPJ-01396 Copy Product Info
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.
PIN4 Protein, Human, Recombinant (His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$727-10 days7-10 days
10 μg$1167-10 days7-10 days
20 μg$1867-10 days7-10 days
50 μg$3527-10 days7-10 days
100 μg$5827-10 days7-10 days
200 μg$9677-10 days7-10 days
500 μg$1,9007-10 days7-10 days
1 mg$2,7307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.
Species
Human
Expression System
E. coli
TagN-6xHis
Accession NumberQ9Y237-2
Amino AcidMet1-Lys156
ConstructionMet1-Lys156
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of PBS, pH7.5.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsRotamase Pin4, PIN4, Peptidyl-prolyl cis-trans isomerase Pin4, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Peptidyl-prolyl cis/trans isomerase EPVH, Parvulin-17, Parvulin-14
Research Background
Chemical Properties
Molecular Weight21 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: PIN4 Protein, Human, Recombinant (His) chemical structure | PIN4 Protein, Human, Recombinant (His) molecular weight