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Anti-IL-1RAPL1 Antibody (6Q74) is a Mouse antibody targeting IL-1RAPL1. Anti-IL-1RAPL1 Antibody (6Q74) can be used in WB,ICC,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $428 | 7-10 days |
Description | Anti-IL-1RAPL1 Antibody (6Q74) is a Mouse antibody targeting IL-1RAPL1. Anti-IL-1RAPL1 Antibody (6Q74) can be used in WB,ICC,FCM. |
Synonyms | TIGIRR-2, OPHN4, MRX34, interleukin 1 receptor accessory protein-like 1, IL1RAPL, IL1R8, C030039N24, 6330532G10Rik |
Reactivity | Human |
Verified Activity | 1. Western blot analysis of IL1RAPL1 on ?human IL1RAPL1 recombinant protein using anti-IL1RAPL1 antibody at 1/1,000 dilution. 2. Western blot analysis of IL1RAPL1 on HEK293 (1) and IL1RAPL1-hIgGFc transfected HEK293 (2) cell lysate using anti-IL1RAPL1 antibody at 1/1,000 dilution. 3. Western blot analysis of IL1RAPL1 on different cell lysate using anti-IL1RAPL1 antibody at 1/1,000 dilution. Positive control: Lane1: A431 Lane2: SK-Hep-1 Lane3: HL-7702 4. ICC staining IL1RAPL1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of Hela cells with IL1RAPL1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
Application | |
Recommended Dose | WB: 1:500-2000; ICC: 1:50-200; FCM: 1:100-200 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Research Background | May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 80 kDa. |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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